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Displaying results 1311 - 1320 of 10000 in total
  1. Drug

    Vigabatrin

    go.drugbank.com/drugs/DB01080
    ApprovedInvestigational

    [A202037] It was first introduced as an antiepileptic agent in the United Kingdom in 1989 and was used extensively until 1997, when an association with vision loss became apparent. … Vigabatrin is an analog of gamma-aminobutyric acid ([GABA]), the main inhibitory neurotransmitter in the central nervous system, used in the treatment of refractory seizures and infantile spasms.

    Products: SABRIL 500 MG 50 SASE, SABRIL 500 MG
  2. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    [A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM).

    Products: REXULTI (BREXPIPRAZOLE) TABLETS 1 MG, REXULTI (BREXPIPRAZOLE) TABLETS 2 MG
  3. Drug

    Tauroursodeoxycholic acid

    go.drugbank.com/drugs/DB08834
    ApprovedInvestigationalWithdrawn

    [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as a bile acid derivative. … Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration.

    Products: TAUROLITE 250 MG 100 KAPSUL
  4. Drug

    Sodium phosphate, monobasic

    go.drugbank.com/drugs/DB09449
    ApprovedInvestigational

    Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.

    Mixtures: AMINOPLASMAL-10% E INFUSION, UroAv-81Products: BT ORAL SOLUSYON 90 ML, FLEET FOSFO-SODA 90 ML SOLUSYON
  5. Drug

    Hydrocortisone

    go.drugbank.com/drugs/DB00741
    ApprovedInvestigationalVet approved

    [A188420] Hydrocortisone was granted FDA approval on 5 August 1952.[L10574] … [L10529,L10532,L10535,L10538,L7772,L7321] It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.

    Mixtures: Activir Duo 50 mg/g + 10 mg/g Creme, Oto End 10Synonyms: Reichstein's substance M, (11β)-11,17,21-trihydroxypregn-4-ene-3,20-dione
  6. Drug

    Chlorzoxazone

    go.drugbank.com/drugs/DB00356
    Approved

    It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)

    Mixtures: MEPADOL TABLET, 20 ADET, MUSKAZON TABLET, 20 ADETProducts: PARAFLEX 250 MG TABLET, 20 ADET, PARAFLEX FORTE TABLET 500 MG, 20 ADET
  7. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    Williams in 1919. … Pantothenic acid is an ingredient in some hair and skin care products.

    Mixtures: B Plus C 300 mg, Stress B With 1000 Mg Vitamin CCategories: Vitamin B Complex
  8. Drug

    Flavoxate

    go.drugbank.com/drugs/DB01148
    Approved

    A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. … It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]

    Synonyms: 2-piperidinoethyl 3-methylflavone-8-carboxylate, β-piperidinoethyl 3-methylflavone-8-carboxylateProducts: FLOVOX® 200 MG, BLADURIL ® 200 MG
  9. Drug

    Abrocitinib

    go.drugbank.com/drugs/DB14973
    ApprovedInvestigational

    [A244549] Abrocitinib was approved by the European Commission on December 10, 2021, for the treatment of moderate-to-severe atopic dermatitis (AD) in adults who are candidates for systemic therapy. … including atopic dermatitis, a chronic inflammatory skin disease with complex pathogenesis.

    Products: CIBINQO® 50 MG, CİBİNQO 50 MG FİLM KAPLI TABLET, 28 ADET
  10. Drug

    Sodium fluoride

    go.drugbank.com/drugs/DB09325
    ApprovedInvestigational

    The use of fluoride in dental practice began in the 1940s. … [L4894] Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated drinking water showed less tooth decay than those without fluoridated

    Mixtures: PREVENT 2 EN 1, TRACUTIL® 10 ML AMPOLLASCategories: Compounds used in a research, industrial, or household setting