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Displaying results 1311 - 1320 of 10000 in total
  1. Drug

    Tuvusertib

    go.drugbank.com/drugs/DB18790
    Investigational

    Synonyms: 2-amino-6-fluoro-N-[5-fluoro-4-(1-methyl-1H-imidazol-5-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
  2. Drug

    Porphobilinogen

    go.drugbank.com/drugs/DB02272
    Experimental

    Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid
  3. Drug

    UDP-alpha-D-xylose

    go.drugbank.com/drugs/DB01713
    Experimental

    The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl hydroxyl groups in mucoprotein synthesis. Also forms plant xylans.

    Synonyms: Uridine-5'-diphosphate-xylopyranose, UDP-alpha-D-xylose
  4. Drug

    Azapropazone

    go.drugbank.com/drugs/DB07402
    ApprovedWithdrawn

    Synonyms: 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine, 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dioneCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    LSP-GR3

    go.drugbank.com/drugs/DB16934
    Experimental

    Synonyms: 2'-O-Methyl Phosphorothioate 5'-GCUAGGUUUACGGGACCUCU-3'
  6. Drug

    Zolimomab aritox

    go.drugbank.com/drugs/DB33667
    Experimental

    Synonyms: Orthozyme cd 5 plus, Xoma zyme h 65Categories: N-Glycosyl Hydrolases, Ribosome Inactivating Proteins, Type 2
  7. Drug

    Afegostat

    go.drugbank.com/drugs/DB04545
    Investigational

    Synonyms: (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diolCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Ertapenem

    go.drugbank.com/drugs/DB00303
    ApprovedInvestigational

    Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics.[L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid
  9. Drug

    Sonrotoclax

    go.drugbank.com/drugs/DB18753
    ApprovedInvestigational

    lines of systemic therapy, including a BTK inhibitor. … Sonrotoclax is a selective, potent, small-molecule inhibitor of BCL-2, an antiapoptotic protein overexpressed in B-cell malignancies.

    Synonyms: N-[4-({[(1r,4r)-4-hydroxy-4-methylcyclohexyl]methyl}amino)-3- nitrobenzene-1-sulfonyl]-4-(2-{(2S)-2-[2-(propan-2-yl)phenyl]pyrrolidin- 1-yl}-7-azaspiro[3.5]nonan-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-5- ylCategories: BCL-2 Inhibitor, P-glycoprotein substrates
  10. Drug

    Deucrictibant

    go.drugbank.com/drugs/DB18303
    Investigational

    Synonyms: Acetamide, N-[(1S)-1-[3-chloro-5-fluoro-2-[[[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5- yl)-8-quinolinyl]oxy]methyl]phenyl]ethyl-1-d]-2-(difluoromethoxy)-, N-[(1S)-1-[3-chloro-5-fluoro-2-({[2-methyl-4-(1-methyl-1H-1,2,4-triazol-5-yl)quinolin-8-yl]oxy}methyl)phenyl](1-2H)ethyl]-2-(difluoromethoxy)acetamide