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Dabigatran etexilate
go.drugbank.com/drugs/DB06695ApprovedInvestigationalDabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor [dabigatran]. … [A177463] In contrast to warfarin, because its anticoagulant effects are predictable, lab monitoring is not necessary.[A177463] Dabigatran etexilate was approved by the FDA in 2010.[L6022]
Categories: Blood and Blood Forming OrgansProducts: Pradaxa 150mg, Hard Capsules, Dabigatran Sandoz Capsule 150mgAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalIt functions by preventing resorption of bone[FDA Label][A959]. … Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: ALENDRON-HEXAL 4 WO CAL D, ALENDRON-HEXAL 12 WO CAL DCategories: alendronic acid and colecalciferol, alendronic acid and alfacalcidol, sequentialCapmatinib
go.drugbank.com/drugs/DB11791ApprovedInvestigational[L13347] The presence of the mutation must be confirmed by an FDA-approved test, such as the FoundationOne CDx assay (manufactured by Foundation Medicine, Inc.), which was approved by the FDA on the same … Manufactured by Novartis and marketed under the brand name Tabrecta, capmatinib was granted accelerated approval by the FDA on May 6, 2020,[L13380] for the treatment of NSCLC in patients whose tumors have
Categories: Antineoplastic and Immunomodulating Agents, MATE 2-K InhibitorsProducts: TABRECTA FILM-COATED TABLET 150mg, Rahika 150mg Film-coated TabletForeign body sensation in eyes
go.drugbank.com/conditions/DBCOND0009657Synonyms: Foreign body sensation in eyes, Foreign body sensation in eyeDecrease in absolut neutrophil count
go.drugbank.com/conditions/DBCOND0102569Synonyms: Decreases in neutrophils, Decreases in neutrophil countBusulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalIt has been used in the palliative treatment of chronic myeloid leukemia (myeloid leukemia, chronic), but although symptomatic relief is provided, no permanent remission is brought about. … Busulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Myleran Tablets 2mg, IV BUSULFEX INJECTIONAtracurium
go.drugbank.com/drugs/DB13295ApprovedInvestigationalWithdrawnProducts: ATRACURIO BESILATO 10MG/ML SOLUCION INYECTABLE, DEMATRAC 25 MG/2.5 ML IV İNFÜZYON İÇİN SOLÜSYON İÇEREN AMPUL, 10 AMPULFremanezumab
go.drugbank.com/drugs/DB14041ApprovedInvestigational[L11749] It was developed by Teva Pharmaceuticals USA and approved by the FDA in September 2018. … [L11779] Along with other recently approved anti-CGRP therapies such as [galcanezumab], [erenumab], and the oral CGRP antagonist [ubrogepant], fremanezumab represents an important step forward in the treatment
Categories: Amino Acids, Peptides, and ProteinsProducts: AJOVY SOLUTION FOR INJECTION IN PRE-FILLED PEN 225 MG/1.5ML, AJOVY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 225 MG/1.5MLIxekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIxekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing. … As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions.
Categories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane AgentsProducts: Taltz 80mg solution for injection in pre-filled pen, Taltz 80mg solution for injection in pre-filled syringeAzacitidine
go.drugbank.com/drugs/DB00928ApprovedInvestigationalOne of them is the induction of cytotoxicity. As an analogue of cytidine, it is able to incorporate into RNA and DNA, disrupting RNA metabolism and inhibiting protein and DNA synthesis. … [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335]
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: Vidaza powder for suspension for injection 100mg/vial, AZADINE POWDER FOR SUSPENSION FOR INJECTION 100MG/VIAL