Search
Baricitinib
go.drugbank.com/drugs/DB11817ApprovedInvestigational[L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018. … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: UNAMİTY 4 MG FİLM KAPLI TABLET, 56 ADET, UNAMİTY 2 MG FİLM KAPLI TABLET, 56 ADETPeppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalDue to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized … Peppermint oil can be applied topically to temporarily relieve tension-type headache.
Synonyms: Peppermint flowering top oil, Mentha piperita flowering top oilMixtures: MENTOSEPTOL GARGARA, 100 ML, BUĞUMENTOL BUĞU, 40 GDexrazoxane
go.drugbank.com/drugs/DB00380ApprovedInvestigationalWithdrawnIt appears to inhibit formation of a toxic iron-anthracycline complex.
International brands: Ao Nuo XianProducts: Cyrdanax 20 mg/ml Pulver zur Herstellung einer InfusionslösungCholine
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Mixtures: Stress B With 1000 Mg Vitamin C, Sentralopram AM-10Products: Choline Bitartrate 500 Mg - Tablet, Choline 250 mgZaleplon
go.drugbank.com/drugs/DB00962ApprovedIllicitZaleplon is a sedative/hypnotic, mainly used for insomnia. It is known as a nonbenzodiazepine hypnotic. Zaleplon interacts with the GABA receptor complex and shares some of the pharmacological properties of the benzodiazepines. Zaleplon ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SONATA © 10 MG CAPSULAS., SONATA ® 5 MG. CAPSULASRotavirus vaccine
go.drugbank.com/drugs/DB10276ApprovedInvestigationalRotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. … [L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains.
Salts: Human Rotavirus A type G1P7(5) strain WI79 live antigen, Human Rotavirus A type G2P7(5) strain SC2 live antigenProducts: ROTARİX 1,5 ML ORAL SÜSPANSİYON (10 TÜP), ROTARIX ORAL SÜSPANSIYON HAZIRLAMAK IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 10 ADETIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigational[L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex. … Ipilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4).
Categories: Immunoglobulin G, Increased T Lymphocyte ActivationProducts: YERVOY 5 mg/ml concentrate for solution for infusion, YERVOY®5 MG /ML SOLUCION INYECTABLE PARA INFUSION INTRAVENOSANifuroxazide
go.drugbank.com/drugs/DB13855InvestigationalMixtures: METRONIDAZOL/NIFUROXAZIDA 300 MG/100 MG., METRONIDAZOL BENZOILO/ NIFUROXAZIDA 250MG + 200MG/5 ML SUSPENSIONProducts: KOFURIL 100 MG KAPSÜL 30 ADET, KOFURIL 100 MG KAPSÜL, 12 ADETTrandolapril
go.drugbank.com/drugs/DB00519ApprovedInvestigationalTrandolapril may be used to treat mild to moderate hypertension, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, as an adjunct treatment … It is metabolized to its biologically active diacid form, trandolaprilat, in the liver.
Mixtures: VERACOMB MR 180/2 MG KAPSÜL, 28 ADET, VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADETProducts: GOPTEN 0,5 MG SERT KAPSUL, 20 ADET, GOPTEN 2 MG KAPSUL, 28 ADETAflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[A261281,A261286] Due to the 2 fused VEGFR, aflibercept has a higher affinity to the cognate ligands than the endogenous individual receptor. … However, it lacks the intracellular structure to propagate subsequent signal transduction, thus essentially sequestering the ligands to prevent activation of VEGFR.
Products: EYLEA 40 MG/ML INTRAVITREAL ENJEKSIYON ICIN COZELTI ICEREN FLAKON, 1 ADET, ZALTRAP 200 MG/8 ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1ADET