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Displaying results 1331 - 1340 of 10000 in total
  1. Drug

    Difenoxin

    go.drugbank.com/drugs/DB01501
    ApprovedIllicit

    It works mostly in the periphery and activates opioid receptors in the intestine rather than the central nervous system (CNS). [3] Difenoxin is also closely related to loperamide, but unlike loperamide … Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. It is approved by the FDA to treat acute and chronic diarrhea.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid
  2. Drug

    Imdevimab

    go.drugbank.com/drugs/DB15940
    ApprovedInvestigational

    [L23524] In November 2021, the same indication was approved by the EMA. … Casirivimab and imdevimab are investigational recombinant human IgG1 monoclonal antibodies that, at this time, are not officially approved by the FDA.

  3. Drug

    Lactic acid

    go.drugbank.com/drugs/DB04398
    ApprovedInvestigationalVet approved

    Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120] … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.

    Synonyms: 2-Hydroxypropanoic acid, 2-Hydroxypropionic acidMixtures: Dextrose and Electrolyte No. 75, Dextrose and Electrolyte No. 48
  4. Drug

    Scopolamine

    go.drugbank.com/drugs/DB00747
    ApprovedInvestigational

    [A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. … [A228773, L31578] Scopolamine was first approved by the FDA on December 31, 1979, and is currently available as both oral tablets and a transdermal delivery system.[L31578]

    Synonyms: alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester, 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropateMixtures: Diban Cap, Diban Cap
  5. Indication

    Congenital Adrenal Hyperplasia (CAH)

    go.drugbank.com/conditions/DBCOND0033416
    Drugs: Betamethasone · Bupivacaine · Cortisone acetate · Crinecerfont · Dexamethasone · Hydrocortisone +7 more
    Synonyms: CAH - Congenital Adrenal Hyperplasia, Congenital Adrenal Hyperplasia (CAH)
  6. Indication

    Coronary Artery Disease (CAD)

    go.drugbank.com/conditions/DBCOND0032937
    Drugs: Amlodipine · Atorvastatin · Gemfibrozil
    Synonyms: CAD, Coronary Artery Disease (CAD)
  7. Drug

    Vayarin

    go.drugbank.com/drugs/DB09328
    Approved

    Vayarin is currently available only by prescription in the USA [L1502]. This drug has also been used for management of hypertriglyceridemia [L1503]. … Vayarin is an orally administered prescription medical food for the clinical dietary management of complex lipid imbalances thought to be associated with ADHD.

    Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  8. Drug

    Acetrizoic acid

    go.drugbank.com/drugs/DB09347
    ApprovedWithdrawn

    [A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978. … [L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status.[L1703]

    Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, Iodinated
  9. Drug

    Arbutamine

    go.drugbank.com/drugs/DB01102
    Approved

    Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in … diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .

    Categories: Compounds used in a research, industrial, or household setting, Adrenergic beta-1 Receptor Agonists
  10. Drug

    Lenalidomide

    go.drugbank.com/drugs/DB00480
    ApprovedInvestigational

    Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. … [A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal

    Synonyms: 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring