Search

Displaying results 1341 - 1350 of 10000 in total
  1. Drug

    Peramivir

    go.drugbank.com/drugs/DB06614
    ApprovedInvestigational

    Peramivir is an antiviral agent developed by Biocryst Pharmaceuticals to treat influenza A/B. … The development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic.

    Products: Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (3 Adet), Influviran 200 mg/20 mL IV İnfüzyonluk Çözelti Hazırlamak İçin Konsantre (5 Adet)
  2. Drug

    Stiripentol

    go.drugbank.com/drugs/DB09118
    ApprovedInvestigational

    [A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated with Dravet syndrome.[L880,L42500,L42510] It is marketed under the brand name Diacomit. … Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.

    Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitorsSynonyms: 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol, 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol
  3. Drug

    Albutrepenonacog alfa

    go.drugbank.com/drugs/DB13884
    Approved

    [A32547] It was developed by CSL Behring Canada, Inc and approved by Health Canada on April 26, 2017. It was also approved by FDA and EMA in 2016. … It is currently marketed in the forms of 250, 500, 1000 and 2000 IU/vial.[L2305]

    Synonyms: Coagulation factor IX (recombinant), albumin fusion protein, Coagulation Factor IX (Recombinant), Albumin Fusion Protein (rIX-FP)Products: IDELVION 250 IU powder and solvent for solution for injection, IDELVION 500 IU powder and solvent for solution for injection
  4. Drug

    Avelumab

    go.drugbank.com/drugs/DB11945
    ApprovedInvestigational

    [A261496] Avelumab was first approved by the FDA on March 23, 2017. … [A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively.

    Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON, BAVENCIO®
  5. Target

    Outer membrane protein TolC

    go.drugbank.com/bio_entities/BE0001931
    TargetEscherichia coli (strain K12)

    Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. ...

    Synonyms: colE1-i
  6. Target

    StAR-related lipid transfer protein 7, mitochondrial

    go.drugbank.com/bio_entities/BE0023326
    TransporterHumans

    Mediates non-vesicular transfer of phosphatidylcholine to mitochondria, thereby maintaining mitochondrial membrane lipid composition, cristae organization, and respiratory function across diverse tissues

    Synonyms: StarD7-I
  7. Drug

    Andexanet alfa

    go.drugbank.com/drugs/DB14562
    Approved

    However, the use of these agents is associated with a risk for uncontrollable bleeding episodes that can lead to can cause serious or fatal bleeding. … Andexanet alfa retains the structural similarity to that of endogenous human factor Xa, but exists in its mature functional form without the need for activation via the intrinsic or extrinsic coagulation

    Synonyms: r-AntidoteCategories: Factor X
  8. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    as compared to other agents in this class. … [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, P-glycoprotein substratesSynonyms: (S)-Citalopram, S(+)-Citalopram
  9. Drug

    Stem bromelain

    go.drugbank.com/drugs/DB12249
    Approved

    This action allows bromelain to demonstrate a wide range of therapeutic benefits ranging from cardiovascular to anticancer therapy - but the specific mechanisms of action by which it can elicit these effects … Bromelain is consequently a composite mixture of several different endopeptidases that can facilitate many different reactions with many different substrates.

  10. Drug

    Zinc sulfate

    go.drugbank.com/drugs/DB09322
    ApprovedInvestigational

    It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".

    Mixtures: Nutrol E-400 Plus Zinc Et Selenium Cap, Clear Eyes Acr By MurineProducts: ZINC GO FORTE, SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE.