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Displaying results 1351 - 1360 of 10000 in total
  1. Drug

    Azilsartan medoxomil

    go.drugbank.com/drugs/DB08822
    ApprovedInvestigational

    It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. … It is also available in a combination product with [chlorthalidone].

    Mixtures: EDARBYCLOR (TABLETS) 40 MG/12.5 MG, EDARBYCLOR (TABLETS) 40 MG/12.5 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  2. Drug

    Methyl aminolevulinate

    go.drugbank.com/drugs/DB00992
    ApprovedInvestigational

    Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

    Synonyms: methyl 5-aminolevulinate, methyl δ-aminolevulinateProducts: METVIX® CREMA 160 MG/G, Luxerm 160 mg/g Creme
  3. Drug

    Etonogestrel

    go.drugbank.com/drugs/DB00294
    ApprovedInvestigational

    Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. … [A37184] The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.[L5692]

    Synonyms: 3-Ketodesogestrel, 3-OxodesogestrelMixtures: Perlinring 0,120 mg/0,015 mg pro 24 Stunden - Vaginalring, NuvaRing 0,120 mg/0,015 mg pro 24 Stunden - Vaginalring
  4. Drug

    Tibolone

    go.drugbank.com/drugs/DB09070
    ApprovedInvestigational

    Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874]. … Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and progestogenic properties.

    Synonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-oneCategories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  5. Drug

    Daclatasvir

    go.drugbank.com/drugs/DB09102
    ApprovedInvestigationalWithdrawn

    Daclatasvir is a direct-acting antiviral agent against Hepatitis C Virus (HCV) used for the treatment of chronic HCV genotype 1 and 3 infection. … Hepatitis C is an infectious liver disease caused by infection with Hepatitis C Virus (HCV).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)
  6. Drug

    Isoflurane

    go.drugbank.com/drugs/DB00753
    ApprovedInvestigationalVet approved

    A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether
  7. Drug

    Osimertinib

    go.drugbank.com/drugs/DB09330
    ApprovedInvestigational

    testing and which has progressed following therapy with a first-generation EGFR tyrosine kinase inhibitor. … Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSynonyms: N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
  8. Drug

    Histamine

    go.drugbank.com/drugs/DB05381
    ApprovedInvestigational

    It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. … A depressor amine derived by enzymatic decarboxylation of histidine.

    Mixtures: Md Science Cannabidiol, Md Science CannabigerolCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  9. Drug

    Sufentanil

    go.drugbank.com/drugs/DB00708
    ApprovedInvestigational

    The sublingual form, manufactured by AcelRx Pharmaceuticals, Inc. (AcelRx), was approved on November 2, 2018 [L4717]. … It is administered by the intravenous, epidural and sublingual routes.

    Synonyms: 舒芬太尼, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Morinamide

    go.drugbank.com/drugs/DB13417
    Investigational

    Products: MORFOZID 500 MG TABLET, 50 ADET, MORFOZID 500 MG TABLET, 500 ADET