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Displaying results 1361 - 1370 of 10000 in total
  1. Drug

    Rasburicase

    go.drugbank.com/drugs/DB00049
    ApprovedInvestigational

    Rasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified Saccharomyces cerevisiae strain. The cDNA coding for rasburicase was cloned from a strain of Aspergillus flavus.

    Products: FASTURTEC®1.5 MG / ML, FASTURTEC 1,5 MG/1 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1 ADET
  2. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic nature [A1351]. … Chloroxylenol is on the World Health Organization's List of Essential Medicines.

    Mixtures: D-COL Personal Hygiene Convenience kit, Oto End 10Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Idarucizumab

    go.drugbank.com/drugs/DB09264
    Approved

    Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its … Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of dabigatran-associated bleeding in life-threatening or surgically induced situations.

    Products: PRAXBIND Solution for Injection/Infusion 50 mg/ml, PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/ML
  4. Drug

    PYX-201

    go.drugbank.com/drugs/DB18382
    Investigational

    PYX-201 is an antibody-drug conjugate directed against the extra domain-B splice variant of fibronectin.

  5. Drug

    NTLA-2002

    go.drugbank.com/drugs/DB17597
    Investigational

    NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. … It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.[L45738]

  6. Drug

    CLZ-2002

    go.drugbank.com/drugs/DB18638
    Investigational

    CLZ-2002 consists of allogeneic mesenchymal stem cells derived neuronal regeneration-promoting cells.

  7. Drug

    Bosentan

    go.drugbank.com/drugs/DB00559
    ApprovedInvestigational

    Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise pr...

    Synonyms: 4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide, p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamideProducts: TRACLEER ® 62.5 MG TABLETAS RECUBIERTAS DE PELICULA., N/A
  8. Drug

    Obinutuzumab

    go.drugbank.com/drugs/DB08935
    ApprovedInvestigational

    [L54521] Like other drugs in its class, obinutuzumab targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes, mediating B-cell lysis. … This chemical modification significantly enhances its affinity for FcγRIII receptors on immune effector cells.

    Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA ® CONCENTRADO PARA SOLUCIÓN PARA INFUSIÓN 1000 MG / VIAL 40 ML
  9. Drug

    Permethrin

    go.drugbank.com/drugs/DB04930
    ApprovedInvestigational

    A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.

    Categories: Compounds used in a research, industrial, or household settingProducts: NOVOHERKLIN 2000, NOVO HERKLIN 2000
  10. Drug

    Pyritinol

    go.drugbank.com/drugs/DB13084
    Investigational

    Pyritinol has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders.

    Products: ENCEFABOL 200 MG, ENCEFABOL® 200 MG SUSPENSION