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Displaying results 1381 - 1390 of 10000 in total
  1. Drug

    Uridine-5'-diphosphate-4-deoxy-4-fluoro-alpha-D-galactose

    go.drugbank.com/drugs/DB04097
    Experimental

    Synonyms: Uridine-5'-diphosphate-4-deoxy-4-fluoro-alpha-D-galactose, UDP-4-fluoro-4-deoxy-alpha-D-glucose
  2. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. … Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation.

    Synonyms: Vitamin B 1, thiamine(1+)International brands: Betalin S
  3. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    Concerta also provides a sustained 10-12 hour effect, allowing for once-daily dosing. … The MLRTM release system allows for a sustained effect for 10-12 hours, allowing for once-daily dosing that covers the major times that ADHD impairment might occur (such as school, homework periods, during

    Synonyms: methyl α-phenyl-α-(2-piperidyl)acetate, methyl α-phenyl-α-2-piperidinylacetateMixtures: MEDIKINET MR, MEDIKINET MR
  4. Drug

    D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide

    go.drugbank.com/drugs/DB02038
    Experimental

    Synonyms: D-[3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-N,O-cycloserylamide, D-pyridoxyl-N,O-cycloserylamide-5-monophosphate
  5. Drug

    DSP-5336

    go.drugbank.com/drugs/DB18514
    Investigational

    DSP-5336 is a menin inhibitor.

    Synonyms: BENZAMIDE, 5-FLUORO-2-((4-(7-(((1S,3S,4R)-5-METHYLENE-2-AZABICYCLO(2.2.2)OCT-3-YL)CARBONYL)-2,7-DIAZASPIRO(3.5)NON-2-YL)-5-PYRIMIDINYL)OXY)-N,N-BIS(1-METHYLETHYL)-
  6. Drug

    Hepcidin-25

    go.drugbank.com/drugs/DB19226
    Investigational

    Hepcidin-25 is under investigation in clinical trial NCT03381833 (A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-dependent Beta Thalassemia).

    Synonyms: Asp-thr-his-phe-pro-ile-cys-ile-phe-cys-cys-gly-cys-cys-his-arg-ser-lys-cys-gly-met-cys-cys-lys-thr (7->23),(10->13),(11->19),(14->22)-tetrakis(disulfide), Hepcidin-25
  7. Drug

    Bazlitoran

    go.drugbank.com/drugs/DB14990
    Investigational

    Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).

    Synonyms: ALL-P-AMBO-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-P-THIOTHYMIDYLYL-(3'->5')-2'-O-METHYL-P-THIOGUANYLYL, -(3'->5')-2'-O-METHYL-P-THIOURIDYLYL-(
  8. Drug

    Amprolium

    go.drugbank.com/drugs/DB11374
    ExperimentalVet approved

    Amprolium is a coccidiostat used in poultry.

    Synonyms: 1-((4-amino-2-Propyl-5-pyrimidinyl)methyl)-2-picolinium chlorideCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    [A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily. … Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin.

    Synonyms: N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamideCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitors
  10. Drug

    Temozolomide

    go.drugbank.com/drugs/DB00853
    ApprovedInvestigational

    [L32033] Temozolomide was granted FDA approval on August 11, 1999, as an oral capsule and subsequently on February 27, 2009, as an intravenous injection. … It is currently marketed under the trademark TEMODAR® by Merck.[L32033]

    Synonyms: 3-methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 8-carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-oneCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substrates with a Narrow Therapeutic Index