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Daclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnThe therapy is intended to cure or achieve a sustained virologic response (SVR12), after 12 weeks of daily therapy. … According to 2017 American Association for the Study of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg [DB08934] for genotype 1a/b patients with or without cirrhosis as second-line
Categories: Antivirals for treatment of HCV infectionsProducts: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)Icosapent ethyl
go.drugbank.com/drugs/DB08887ApprovedInvestigationalNutraceuticalFDA approved on July 26, 2012. … Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA).
Temoporfin
go.drugbank.com/drugs/DB11630ApprovedTemoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label].
Categories: Heterocyclic Compounds with 4 or More RingsTibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalTibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and progestogenic properties. … It has been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis and the treatment of post-menopausal symptoms [L1720].
Categories: Sex Hormones and Modulators of the Genital SystemProducts: LIVIAL TABLET 2.5 mg, TINOX 2.5 MG TABLETADiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawn(Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942] … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen.
Categories: Sex Hormones and Modulators of the Genital SystemProducts: Stilbestrol Tablets 1.0 mg, Stilbestrol Tablets 0.1 mgCefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigational[A180739] Because of its chemical structure, it is effective against organisms that are resistant to first-line cephalosporin therapy due to the production of beta-lactamase enzymes.[A180724,A180727] … It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin.
Mixtures: FULLCEF PLUS 125 MG/62.5 MG SAŞE, 20 ADET, FULLCEF PLUS 300 MG/125 MG EFERVESAN TABLET, 20 ADETProducts: CEFDIAL® 250 MG, ASEMAX 300 MG FILM TABLET, 14 ADETBeremagene geperpavec
go.drugbank.com/drugs/DB17831ApprovedInvestigationalDeveloped by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). … [A259771] Beremagene geperpavec is genetically modified to deliver _COL7A1_, thereby restoring the levels of the COL7 protein.[L46551]
Categories: Preparations for Treatment of Wounds and UlcersSpinosad
go.drugbank.com/drugs/DB08823ApprovedVet approvedSpinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults … Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species.
Categories: Compounds used in a research, industrial, or household settingMilnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigationalyet approved the agent for such treatment, citing lack of robust evidence of efficacy, insufficient demonstration of maintenance of effect, and other concerns [F3928, F3934]. … Moreover, recent research has shown that the levorotatory enantiomer of milnacipran, levomilnacipran, may have the capacity to inhibit the activity of beta-site amyloid precursor protein cleaving enzyme
Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Ixel 25 mg - Kapseln, Ixel 50 mg - KapselnTannic acid
go.drugbank.com/drugs/DB09372ApprovedInvestigationalTannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine. … It is a type of the commercially available tannins. It acts as a weak acid.
Categories: Compounds used in a research, industrial, or household setting