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Displaying results 131 - 140 of 144679 in total
  1. Drug

    Hydralazine

    go.drugbank.com/drugs/DB01275
    ApprovedInvestigational

    [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed.

    Salts: Hydralazine hydrochlorideMixtures: Isosorbide dinitrate and hydralazine hydrochloride, Isosorbide Dinitrate and Hydralazine Hydrochloride
  2. Drug

    Quinoline Yellow WS

    go.drugbank.com/drugs/DB14231
    Experimental

    Synonyms: D and C Yellow No. 10, D&C Yellow No. 10
  3. Drug

    Labetalol

    go.drugbank.com/drugs/DB00598
    ApprovedInvestigational

    [L7730] Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.[L7724]

    Salts: Labetalol hydrochlorideCategories: Alpha and Beta Blocking Agents and Thiazides, labetalol and thiazides
  4. Drug

    Tifcemalimab

    go.drugbank.com/drugs/DB18914
    Investigational

    Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)).

    Synonyms: Immunoglobulin g4, anti-(human b and t lymphocyte attenuator (btla)) (human-mus musculus monoclonal js004 .gamma.4-chain), disulfide with human-mus musculus monoclonal js004 .kappa.-chain, dimer
  5. Drug

    TP-3654

    go.drugbank.com/drugs/DB18109
    Investigational

    Synonyms: 2-(trans-4-((3-(3-(trifluoromethyl)phenyl)imidazo[1,2-b]pyridazin6-yl)amino)cyclohexyl)propan-2-ol hydrochlorideSalts: TP-3654 hydrochloride
  6. Drug

    Clonidine

    go.drugbank.com/drugs/DB00575
    ApprovedInvestigational

    Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD.

    Salts: Clonidine hydrochlorideCategories: clonidine and diuretics, Antiglaucoma Preparations and Miotics
  7. Drug

    Lym-1-I-131

    go.drugbank.com/drugs/DB17445
    Experimental

    Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.

    Synonyms: Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma
  8. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    ) receptor, and as an inhibitor of serotonin and norepinephrine uptake. … contraction of HIV and Hepatitis C and other complications including skin infections, abscesses, or endocarditis.

    Salts: Methadone hydrochlorideProducts: Methadone Hydrochloride, Methadone hydrochloride
  9. Drug

    Etigilimab

    go.drugbank.com/drugs/DB18854
    Investigational

    Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).

    Synonyms: Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized mouse monoclonal omp-313m32 .gamma.1-chain), disulfide with humanized mouse monoclonal omp-313m32
  10. Drug

    Olopatadine

    go.drugbank.com/drugs/DB00768
    Approved

    An ophthalmic solution of olopatadine was approved by the FDA and European Union for the treatment of seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. … Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions.

    Salts: Olopatadine hydrochlorideMixtures: Ryaltris (Olopatadine hydrochloride 600mcg/Mometasone furoate 25mcg) Nasal Spray