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Methylprednisolone
go.drugbank.com/drugs/DB00959ApprovedInvestigationalVet approvedMethylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s. Methylprednisolone was granted FDA approval on 24 October 1957. In the outbre...
Mixtures: P-Care D80, P-Care D40Categories: P-glycoprotein inducers, P-glycoprotein substratesDihydroergotamine
go.drugbank.com/drugs/DB00320ApprovedInvestigationalA 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable s...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Dihydergot 2,5 mg - TablettenFludrocortisone
go.drugbank.com/drugs/DB00687ApprovedInvestigationalFludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency. It is functionally similar to aldosterone, the body's primary ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Astonin - H - TablettenCefotaxime
go.drugbank.com/drugs/DB00493ApprovedInvestigationalCefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to c...
Products: Cefotaxim-MIP 1 g - Pulver zur Herstellung einer Injektions- oder Infusionslösung, Cefotaxim-MIP 2 g - Pulver zur Herstellung einer Injektions- oder InfusionslösungMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these form...
Mixtures: Metoprolol "ratiopharm" compositum - TablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTravoprost
go.drugbank.com/drugs/DB00287ApprovedInvestigationalTravoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike ...
Mixtures: Duotrav Pq, Apo-travoprost-timop PqProducts: LUXAGOT PF, TRAVOPROST PH&T EYE DROPS SOLUTION 40MCG/MLBisoprolol
go.drugbank.com/drugs/DB00612ApprovedInvestigationalBisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure. It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive dr...
Mixtures: Concor AMLO 5 mg/5 mg - Tabletten, Concor AMLO 10 mg/5 mg - TablettenCategories: P-glycoprotein inhibitors, P-glycoprotein substratesTriprolidine
go.drugbank.com/drugs/DB00427ApprovedFirst generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Mixtures: Histex-PE, TRIDIN-P SYRUPSynonyms: (E)-2-[3-(1-pyrrolidinyl)-1-p-toluenepropenyl]pyridine, trans-1-(2-pyridyl)-3-pyrrolidino-1-p-tolylprop-1-eneYohimbine
go.drugbank.com/drugs/DB01392ApprovedInvestigationalVet approvedWithdrawnA plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: Yocon-Glenwood Tabletten 5 mgFluoride ion
go.drugbank.com/drugs/DB11257ApprovedInvestigationalHaving a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amoun...
Products: Topex Neutral pH Fluoride Gel Mint, Topex Neutral pH Fluoride Gel Strawberry