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Fentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approvedFentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. Because of these characteristics, fentanyl is commonly used to treat chronic cancer pain or in anesthesia.[Label,L6598,L6601,L66...
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: FENTANYL-PF 100 MCG/2 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 10 ADET, FENTANYL-PF 500 MCG/10 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADETBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states inclu...
Mixtures: Betamethasone Combo 6mg/mL PF, Betamethasone Combo 6mg/mL PFCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesMetformin
go.drugbank.com/drugs/DB00331ApprovedInvestigationalMetformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...
Products: Pg-metformin, KETAMET-PRAdenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigationalThe structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though i...
Mixtures: The Prestige BB SPF25 PA 2Plus, Absolute Total BB SPF37 PA 3PlusCategories: Purinergic P1 Receptor AgonistsAsciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigationalAsciminib is a tyrosine kinase inhibitor (TKI) used in the treatment of chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). … [L39005] It has also shown benefit in Ph+ CML with the T315I mutation, which produces a mutant BCR-ABL1 which is typically treatment-resistant as compared to wild-type BCR-ABL1.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesRaxibacumab
go.drugbank.com/drugs/DB08902ApprovedInvestigationalRaxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons.
Synonyms: PA mAbChlorhexidine
go.drugbank.com/drugs/DB00878ApprovedInvestigationalVet approvedWithdrawnChlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous memb...
Synonyms: 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)Products: Dermsafe Pc, (LAVADO ANTISEPTICO DE MANOS Y CUERPO CON GLUCONATO DE CLORHEXIDINA AL 2% P/P FRASCOMorphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though th...
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: Astramorph PFLidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedEver since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs...
Mixtures: P-Care X, PM ExternalCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesAluminum hydroxide
go.drugbank.com/drugs/DB06723ApprovedInvestigationalSubsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.