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Displaying results 131 - 140 of 2950 in total
  1. Drug

    Nemvaleukin alfa

    go.drugbank.com/drugs/DB18187
    Investigational

    Synonyms: human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2, receptor α-chain fragment (139-303), produced in Ch
  2. Drug

    OriCar-017

    go.drugbank.com/drugs/DB17280
    Investigational

    Synonyms: chimeric antigen receptor (CAR)-T cell therapy targeting G protein-coupled receptor class-C group-5 member-D (GPRC5D)
  3. Drug

    Meperidine

    go.drugbank.com/drugs/DB00454
    ApprovedInvestigational

    A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more...

    Categories: NMDA Receptor Antagonists, P-glycoprotein substratesProducts: Pethidine HCl Fresenius PF 50mg/ml Injection
  4. Drug

    MP-0250

    go.drugbank.com/drugs/DB17218
    Investigational

    Synonyms: Designed ankyrin repeat protein (MP0250)
  5. Drug

    Sodium fluorophosphate

    go.drugbank.com/drugs/DB09484
    ApprovedInvestigational

    Sodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.

    Mixtures: Luster Premium White AM/PMProducts: Vita Fresh, Dental Clinic 2080 Vita Care
  6. Drug

    PMC-403

    go.drugbank.com/drugs/DB18132
    Investigational

    PMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.

    Synonyms: a fully human monoclonal antibody that binds and activates the Tie2 receptor
  7. Drug

    Lerodalcibep

    go.drugbank.com/drugs/DB19071
    ApprovedInvestigational

    Lerodalcibep is a recombinant fusion protein that binds to and inhibits proprotein convertase subtilisin kexin type 9 (PCSK9). PCSK9 is a protein that binds to and promotes the degradation of low-density lipoprotein receptors (LDLRs), wh...

    Synonyms: Engineered binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum
  8. Drug

    Palopegteriparatide

    go.drugbank.com/drugs/DB18676
    ApprovedInvestigational

    Palopegteriparatide is a prodrug consisting of PTH(1-34) conjugated to a methoxy polyethylene glycol carrier (mPEG) via a proprietary TransCon Linker.

    Synonyms: Human parathyroid hormone (PTH) synthetic peptide fragment (1-34), conjugated at the N-terminal amino group via a cleavable linker to O-methylpolyethylene glycol (2 x 20 kDa mPEG); 2-methylalanyl-(1-34
  9. Drug

    Brimonidine

    go.drugbank.com/drugs/DB00484
    ApprovedInvestigational

    [A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. … [A178969] The ophthalmic solution of brimonidine was first approved by the FDA in 1996 as Alphagan [label] and brimonidine is the only selective alpha-adrenergic receptor agonist approved for chronic treatment

    Mixtures: Brim-Dor PF, Tim-Brim-Dor PFCategories: Adrenergic alpha-2 Receptor Agonists
  10. Drug

    Levomenthol

    go.drugbank.com/drugs/DB00825
    ApprovedInvestigational

    Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-oc...

    Mixtures: POMADA VILA, Sarna PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates