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Displaying results 1401 - 1410 of 2816 in total
  1. Drug

    Epofolate

    go.drugbank.com/drugs/DB12266
    Investigational

    Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer...

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  2. Drug

    Aducanumab

    go.drugbank.com/drugs/DB12274
    ApprovedInvestigational

    Aducanumab, or BIIB037, is a monoclonal IgG1 antibody that targets extracellular amyloid-β plaques in the brain; similar to gantenerumab, bapineuzumab and solanezumab. Aducanumab is a recombinant antibody derived from patients with slow ...

  3. Drug

    Lynestrenol

    go.drugbank.com/drugs/DB12474
    ApprovedWithdrawn

    Lynestrenol is a progestin and prodrug of norethisterone.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  4. Drug

    1,2-Benzodiazepine

    go.drugbank.com/drugs/DB12537
    ApprovedInvestigationalWithdrawn

    Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tr...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  5. Drug

    Piperine

    go.drugbank.com/drugs/DB12582
    Investigational

    Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors
  6. Drug

    Lurbinectedin

    go.drugbank.com/drugs/DB12674
    ApprovedInvestigational

    Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma, chronic lymphocytic leukemia (CLL), breast cancer, and small-cell lung cancer (SCLC). It is a derivative...

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  7. Drug

    Ritanserin

    go.drugbank.com/drugs/DB12693
    Investigational

    Ritanserin has been used in trials studying the treatment of Cocaine-Related Disorders.

    Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  8. Drug

    Azamulin

    go.drugbank.com/drugs/DB20304
    Experimental

    Azamulin is a small molecule drug. Azamulin has a monoisotopic molecular weight of 478.26 Da.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  9. Drug

    Burapitant

    go.drugbank.com/drugs/DB20607
    Experimental

    The usage of the INN stem '-pitant' in the name indicates that Burapitant is a neurokinin NK1​ (substance P) receptor antagonist. Burapitant has a monoisotopic molecular weight of 681.2 Da.

  10. Drug

    Aldesleukin

    go.drugbank.com/drugs/DB00041
    ApprovedInvestigational

    Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 ge...

    Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A Inhibitors