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Cilomilast
go.drugbank.com/drugs/DB03849InvestigationalFollowing four clinical trials, the drug proved to be effective in treating COPD, however it has never been marketed due to a poor side effect profile. … Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of respiratory disorders such as asthma and Chronic Obstructive Pulmonary Disease (COPD).
Delamanid
go.drugbank.com/drugs/DB11637ApprovedInvestigationalEmergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for patients, as the disease is associated with a higher mortality rate and insufficient therapeutic … In a clinical study involving patients with pulmonary multidrug-resistant tuberculosis or extensively drug-resistant tuberculosis, treatment of delamanid in combination with WHO-recommended optimised background
Categories: Antiinfectives for Systemic Use, Drugs for Treatment of TuberculosisPaltusotine
go.drugbank.com/drugs/DB16277ApprovedInvestigational[A274476] Paltusotine was approved by the FDA on September 25, 2025 for the treatment of acromegaly in adults.[L54061] … Paltusotine is a selective somatostatin receptor agonist: It mimics the biological actions of endogenous somatostatin, which activates the somatostatin 2 receptor (SST2) to block the secretion of growth
Baloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseMoxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnMoxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. … It is suggested to be effective in cases where other agents such as thiazides, beta-blockers, ACE inhibitors, and calcium channel blockers are not appropriate or irresponsive.
Products: MOXONIDIN 1A PHARMA 0.2MG, MOXONIDIN 1A PHARMA 0.3MGSilodosin
go.drugbank.com/drugs/DB06207ApprovedInvestigationalneck, prostate, and prostatic urethra: the α<sub>1A</sub> subtype accounts for approximately 75% of α1-adrenoceptors in the prostate. … It is indicated for the symptomatic treatment of benign prostatic hyperplasia in adults.
Products: SILODOSIN AL 4 MG HKP, SILODOSIN AL 8 MG HKPRaxibacumab
go.drugbank.com/drugs/DB08902ApprovedInvestigationalRaxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. … Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Synonyms: PA mAbCategories: Antiinfectives for Systemic UseDiethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedEvery year, DEET formulations are used to protect populations from mosquito-borne illnesses like West Nile Virus, the Zika virus, malaria, and/or tick-borne illnesses like Lyme disease and Rocky Mountain
Categories: Compounds used in a research, industrial, or household settingCefoxitin
go.drugbank.com/drugs/DB01331ApprovedInvestigationalCefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by <i>Streptomyces lactamdurans</i>.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cefoxitin for Injection, Cefoxitin for Injection USPCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10584ApprovedInvestigationalMixtures: , Suspension for Injection, ADACEL SUSPENSION FOR INJECTIONCategories: Antiinfectives for Systemic Use