Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Brand Names
Adacel, Boostrix, Daptacel, Diphtheria and Tetanus Toxoids Adsorbed, Infanrix, Kinrix, Pediarix, Pentacel, Quadracel, Td Adsorbed, Tdvax, Tenivac, Vaxelis
Generic Name
Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)
DrugBank Accession Number
DB10584
Background

Not Available

Type
Biotech
Groups
Approved, Investigational
Biologic Classification
Vaccines
Inactivated
Synonyms
  • Diphtheria toxoid
  • Diphtheria toxoid adsorbed

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbataceptThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Abatacept.
AdalimumabThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Adalimumab.
AldesleukinThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Aldesleukin.
AlefaceptThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Alefacept.
AlemtuzumabThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Alemtuzumab.
AltretamineThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Altretamine.
AmsacrineThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Amsacrine.
AnakinraThe therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Anakinra.
Antilymphocyte immunoglobulin (horse)The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Antilymphocyte immunoglobulin (horse).
Antithymocyte immunoglobulin (rabbit)The therapeutic efficacy of Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) can be decreased when used in combination with Antithymocyte immunoglobulin (rabbit).
Interactions
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Food Interactions
Not Available

Products

Products
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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Diphtheria ToxoidLiquid50 lf / mLSubcutaneousAventis Pasteur Limited1925-12-312001-07-19Canada flag
Diphtheria Toxoid for Reaction Test 0.2lf/mlLiquid0.2 lf / mLIntradermalAventis Pasteur Limited1955-01-012000-04-06Canada flag
Diphtheria Toxoid for Schick Control 0.2lf/mlLiquid0.2 lf / mLIntradermalConnaught Laboratories Ltd.1925-12-311996-09-10Canada flag
Diphtheria Toxoid Immunization Of ReactorsLiquid4 lf / mLSubcutaneousAventis Pasteur Limited1933-12-312001-07-19Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ADACELCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5ml) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg/0.5ml) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (3 mcg/0.5ml) + Bordetella pertussis toxoid antigen (formaldehyde inactivated) (2.5 mcg/0.5ml) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (1.5 mg/0.5ml)Injectionบริษัท ซาโนฟี่ ปาสเตอร์2012-06-27Not applicableThailand flag
ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADETCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 mcg/0.5mL) + Bordetella pertussis pertactin antigen (3 mcg/0.5mL) + Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (2.5 mcg/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 Lf/0.5mL)Injection, solutionIntramuscularSANOFİ PASTEUR AŞI TİC. A.Ş.2020-08-14Not applicableTurkey flag
ADACEL 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 5 ADETCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 mcg/0.5mL) + Bordetella pertussis pertactin antigen (3 mcg/0.5mL) + Bordetella pertussis toxoid antigen (glutaraldehyde inactivated) (2.5 mcg/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 Lf/0.5mL)Injection, solutionIntramuscularSANOFİ PASTEUR AŞI TİC. A.Ş.2020-08-14Not applicableTurkey flag
ADACEL POLIO 0,5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 mcg/0.5mL) + Bordetella pertussis pertactin antigen (3 mcg/0.5mL) + Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (2.5 mcg/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 Lf/0.5mL) + Poliovirus type 1 antigen (formaldehyde inactivated) (40 DU/5mL) + Poliovirus type 2 antigen (formaldehyde inactivated) (8 DU/5mL) + Poliovirus type 3 antigen (formaldehyde inactivated) (32 DU/5mL)Injection, suspensionIntramuscularSANOFİ PASTEUR AŞI TİC. A.Ş.2020-08-14Not applicableTurkey flag
Adacel TDaPCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 [Lf]/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 ug/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 ug/0.5mL) + Bordetella pertussis pertactin antigen (3 ug/0.5mL) + Bordetella pertussis toxoid antigen (glutaraldehyde inactivated) (2.5 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [Lf]/0.5mL)Injection, suspensionIntramuscularSanofi Pasteur Inc.2005-06-10Not applicableUS flag
Adacel TDaP TDaPCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 [Lf]/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 ug/0.5mL) + Bordetella pertussis fimbriae 2/3 antigen (5 ug/0.5mL) + Bordetella pertussis pertactin antigen (3 ug/0.5mL) + Bordetella pertussis toxoid antigen (glutaraldehyde inactivated) (2.5 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [Lf]/0.5mL)Injection, suspensionIntramuscularRemedy Repack2015-11-142016-03-29US flag
Bio TdCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 Lf/0.5ml) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (7.5 Lf/0.5ml)Injection, suspensionบริษัท ไบโอวาลิส จำกัด2016-02-24Not applicableThailand flag
BOOSTAGENCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2 mg) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (5 mcg) + Bordetella pertussis toxoid antigen (formaldehyde inactivated) (5 mcg) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (7.5 mg)Injection, suspensionบริษัท ไบโอเนท - เอเชีย จำกัด2019-04-24Not applicableThailand flag
BoostrixCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2.5 [iU]/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (2.5 ug/0.5mL) + Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [iU]/0.5mL)SuspensionIntramuscularA-S Medication Solutions2009-07-24Not applicableUS flag
BoostrixCorynebacterium diphtheriae toxoid antigen (formaldehyde inactivated) (2.5 [iU]/0.5mL) + Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated) (8 ug/0.5mL) + Bordetella pertussis pertactin antigen (formaldehyde inactivated) (2.5 ug/0.5mL) + Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated) (8 ug/0.5mL) + Clostridium tetani toxoid antigen (formaldehyde inactivated) (5 [iU]/0.5mL)SuspensionIntramuscularGlaxoSmithKline Biologicals SA2009-07-24Not applicableUS flag

Categories

ATC Codes
J07AF01 — Diphtheria toxoid
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
IRH51QN26H
CAS number
308079-75-6

References

General References
Not Available
RxNav
235600

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Active Not RecruitingPreventionHuman Papillomavirus Infections / Human Papillomavirus-Related Cervical Carcinoma1
4CompletedNot AvailableDisseminated Sclerosis1
4CompletedPreventionAcellular Pertussis / Diphtheria / Diphtheria-Tetanus-acellular Pertussis Vaccines / Tetanus1
4CompletedPreventionAcellular Pertussis / Diphtheria / Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b Vaccines / Haemophilus Influenzae Type B / Poliomyelitis / Tetanus / Viral Hepatitis B1
4CompletedPreventionAcellular Pertussis / Diphtheria / Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b Vaccines / Poliomyelitis / Tetanus1
4CompletedPreventionAcellular Pertussis / Diphtheria / Haemophilus Influenzae Type B / Poliomyelitis / Tetanus / Viral Hepatitis B2
4CompletedPreventionAcellular Pertussis / Diphtheria / Poliomyelitis / Tetanus / Viral Hepatitis B1
4CompletedPreventionAcellular Pertussis / Diphtheria / Tetanus5
4CompletedPreventionBCG Infection / Immune Responses / Vaccine Reaction1
4CompletedPreventionDiphtheria-Tetanus-acellular Pertussis Vaccines1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection
SuspensionIntramuscular
Injection, suspensionIntramuscular
LiquidIntramuscular
LiquidSubcutaneous50 lf / mL
LiquidIntradermal0.2 lf / mL
LiquidSubcutaneous4 lf / mL
Injection, suspensionParenteral
Injection, powder, for suspensionIntramuscular
SolutionIntramuscular
Injection, solutionIntramuscular
Injection, suspensionIntramuscular; Subcutaneous
InjectionIntramuscular
Injection, suspension
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on December 01, 2015 20:04 / Updated on July 24, 2021 14:58