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Maltose
go.drugbank.com/drugs/DB03323InvestigationalA dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Categories: Compounds used in a research, industrial, or household settingSynonyms: D-(+)-maltoseVasopressin
go.drugbank.com/drugs/DB00067ApprovedInvestigationalthrough V<sub>1</sub> and V<sub>2</sub> cellular receptors. … [A228013] It is currently marketed under the trademark VASOSTRICT® by PAR Pharmaceuticals.[L31413]
Products: VASOPRESSIN INJECTION USP 20 u/ml, VASOPRESINA INYECTABLE 20 U/ML USPCorticosterone
go.drugbank.com/drugs/DB04652Investigational(From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) … An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: Kendall's compound B, Reichstein's substance HMesalazine
go.drugbank.com/drugs/DB00244ApprovedInvestigationalThroughout the late seventies and the eighties, important research initiatives developed stable mesalazine formulations like the eudragit-S coating of Asacol brand mesalazine and the Pentasa brand's encapsulation … Although demonstrably effective in treating and maintaining remission for ulcerative colitis, mesalazine has historically faced a number of issues regarding its lack of stability as a pharmaceutical agent
Synonyms: 3-carboxy-4-hydroxyaniline, 5-ASAProducts: sF Rowasa, PENTASA® ENEMA 1 GVinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) [L1998].
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 5'-NoranhydrovinblastineVigabatrin
go.drugbank.com/drugs/DB01080ApprovedInvestigationalAlthough administered as a racemic mixture, only the S(+) enantiomer is pharmacologically active. … [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual
Categories: Cytochrome P-450 CYP2C9 Inducers, Cytochrome P-450 Enzyme InducersSynonyms: 4-Amino-5-hexenoic acidHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L8072] It was developed during World War II as a derivative of [quinacrine] with less severe side effects.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineAfizagabar
go.drugbank.com/drugs/DB21439InvestigationalAfizagabar is a small molecule drug. Afizagabar is under investigation in clinical trial NCT02877615 (Efficacy and Safety Trial With S 44819 After Recent Ischemic Cerebral Event). … Afizagabar has a monoisotopic molecular weight of 365.06 Da.
Categories: GABA-A Receptor Antagonists, Heterocyclic Compounds, 1-RingNicoboxil
go.drugbank.com/drugs/DB12911ApprovedWithdrawnDespite topical nicoboxil/nonivamide topical analgesic medication being used since the 1950s, recent studies demonstrate continued interest in the medication(s) given its demonstrated efficacy, safety, … Nevertheless, it is predominantly found paired with nonivamide as a combination topical analgesic product where its proposed mechanism of action as a rubefacient is complementary and ultimately synergistic
Mixtures: Nonivamid + Nicoboxil Zentiva 4 mg/g + 25 mg/g SalbeCategories: Heterocyclic Compounds, 1-Ring