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Displaying results 1421 - 1430 of 2250 in total
  1. Target

    NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0000493
    TargetHumans

    Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903 … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-75kD
  2. Target

    Translocation protein SEC62

    go.drugbank.com/bio_entities/BE0009211
    TargetPlasmodium falciparum (isolate 3D7)

    Synonyms: Secretory complex protein 62
  3. Drug

    Navamepent

    go.drugbank.com/drugs/DB21096
    Investigational

    Navamepent is under investigation in clinical trial NCT02329743 (Efficacy and Safety of RX-10045 Ophthalmic Solution for Ocular Inflammation and Pain in Cataract Surgery).

  4. Drug

    Aniline

    go.drugbank.com/drugs/DB06728
    Investigational

    Aniline is colorless, but it slowly oxidizes and resinifies in air, giving a red-brown tint to aged samples.

  5. Drug

    Lomitapide

    go.drugbank.com/drugs/DB08827
    Approved

    Lomitapide, marketed under the brand names Juxtapid (USA) and Lojuxta (EU), is a first-in-class, small-molecule inhibitor of microsomal triglyceride transfer protein (MTP).

  6. Drug

    Rezafungin

    go.drugbank.com/drugs/DB16310
    ApprovedInvestigational

    [L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745]

  7. Drug

    Alfimeprase

    go.drugbank.com/drugs/DB04919
    Investigational

    It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.

  8. Drug

    Liposomal prostaglandin E1

    go.drugbank.com/drugs/DB05391
    Investigational

    Liposome-encapsulated form of prostaglandin E1 (Liprostin) is known to be a potent vasodilator and platelet inhibitor as well as an anti-inflammatory and anti-thrombotic agent.

    Synonyms: Liposomal prostaglandin E1
  9. Drug

    Bizalimogene ralaplasmid

    go.drugbank.com/drugs/DB16113
    Investigational

    Bizalimogene ralaplasmid is under investigation in clinical trial NCT03499795 (VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 And/or HPV-18 Related

    Categories: Complex Mixtures
  10. Drug

    Setmelanotide

    go.drugbank.com/drugs/DB11700
    ApprovedInvestigational

    Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such a...