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Clonidine
go.drugbank.com/drugs/DB00575ApprovedInvestigationalClonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD. … [L7237,L54536,L7240,L7243,L7246] Clonidine was granted FDA approval on 3 September 1974.[L7237]
Categories: Sympathomimetics in Glaucoma TherapySynonyms: 2,6-Dichloro-N-2-imidazolidinylidenebenzenamineGlymidine
go.drugbank.com/drugs/DB01382ApprovedThe mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral … This increase in intracellular calcium ion concentration induces the secretion of insulin.
Categories: Drugs Used in DiabetesMechlorethamine
go.drugbank.com/drugs/DB00888ApprovedInvestigationalThe hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage. … ) in patients who have received prior skin-directed therapy.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2,2'-dichloro-N-methyldiethylamine, N-methyl-bis(2-chloroethyl)amineStreptococcus pneumoniae type 33f capsular polysaccharide antigen
go.drugbank.com/drugs/DB10341ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: PNEUMOVAX 23 Injektionslösung in einer Fertigspritze, PNEUMOVAX 23 Injektionslösung in einer DurchstechflascheBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed by the US approval in October, 2018. … Baloxavir marboxil is an antiviral drug used to treat influenza. More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Hydroquinone
go.drugbank.com/drugs/DB09526ApprovedInvestigationalAs a result of these concerns, hydroquinone has been banned in the EU and UK. … It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.
Mixtures: Phaze 13 Light N' Block Pigment CreamCategories: Compounds used in a research, industrial, or household settingViloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawn[L41685] For decades, an immediate-release formulation of viloxazine has been used in Europe as an antidepressant. … In the US, viloxazine was assigned an orphan drug designation in 1984 under the brand name CATATROL: while this product was intended to treat cataplexy and narcolepsy, the drug was never approved for these
Covax-19™
go.drugbank.com/drugs/DB15846InvestigationalIt uses an insect-cell-produced recombinant SARS-CoV-2 spike protein and Vaxine’s adjuvant, Advax-SM. … As of June 2020, the vaccine is in Phase 1 trials to evaluate safety and immune responses (NCT04428073).
Technetium Tc-99m disofenin
go.drugbank.com/drugs/DB09164ApprovedWithdrawnIt is available as an intravenous injection in a preparation kit under the name Hepatolite. … Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes.
Categories: Compounds used in a research, industrial, or household settingStreptococcus pneumoniae type 12f capsular polysaccharide antigen
go.drugbank.com/drugs/DB10331ApprovedInvestigationalIt is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Mixtures: PNEUMOVAX 23 Injektionslösung in einer Fertigspritze, PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche