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Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalCalcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. … It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement.
Synonyms: calcium(2+) chlorideInternational brands: LiquiCal-D 400Edaravone
go.drugbank.com/drugs/DB12243ApprovedInvestigational[A19140,L44007,A254257] The intravenous formulation of edaravone was first approved in Japan in 2001 for the treatment of acute ischemic stroke. … [L44007] It was later approved for the treatment of amyotrophic lateral sclerosis (ALS) in Japan and South Korea in 2015, followed by the FDA approval in May 2017 [L41810] and Health Canada approval in
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingSynonyms: 1-phenyl-3-methyl-5-oxo-2-pyrazoline, 3-methyl-1-phenyl-2-pyrazolin-5-oneFelodipine
go.drugbank.com/drugs/DB01023ApprovedIt acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity.
Synonyms: 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, (±)-ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylateMixtures: DELMUNO 5/5 MG, TRIAPIN 5/5MGMavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalIt received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. … Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM).
Synonyms: 6-(((1S)-1-Phenylethyl)amino)-3-(propan-2-yl)-1,2,3,4 tetrahydropyrimidine-2,4-dioneCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesActivated charcoal
go.drugbank.com/drugs/DB09278ApprovedInvestigationalIt works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. … The clinical applications of activated charcoal occured in the early 1800's.
Mixtures: FINIGAX®, FINIGAX® CAPSULASCategories: Compounds used in a research, industrial, or household settingAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigationalAcetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488]
Synonyms: N-AC, N Acetyl L CysteineMixtures: AMINOPLASMAL 15% IN 500ML GLASS BOTTLE, N-ACETILCISTEÍNA MAS GUAYACOLATO DE GLICERILOTadalafil
go.drugbank.com/drugs/DB00820ApprovedInvestigationalTadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. … In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and a longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment
Synonyms: (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dioneMixtures: TADA PLUS 30/20 MG FILM KAPLI TABLET ,4 ADET, TADA PLUS 30/20 MG FILM KAPLI TABLET ,8 ADETCholecystokinin
go.drugbank.com/drugs/DB08862ApprovedInvestigationalWithdrawnRecent studies have suggested that cholecystokinin also plays a major role in inducing drug tolerance to opioids such as morphine and heroin, and is partially implicated in experiences of pain hypersensitivity … This hormone has also been shown to have positive effects on enteric smooth muscle contraction and on nerve activity at multiple locations in the peripheral and central nervous system.
Products: Cholecystokinin Inj 75unit/vialEthanolamine oleate
go.drugbank.com/drugs/DB06689ApprovedIt is composed of ethanolamine, a basic substance, which when combined with oleic acid forms a clear, straw to pale yellow colored, deliquescent oleate. … Ethanolamine oleate is a mild sclerosing agent.
Synonyms: Oleate de monoethanolamine, Oleato de monoetanolaminioCategories: Compounds used in a research, industrial, or household settingPyridostigmine
go.drugbank.com/drugs/DB00545ApprovedInvestigationalPossible dose forms have been expanded to include extended-release tablets, syrups, and injections, marketed under various brand and generic names.[L32408, L32413] … [L32408, L32413] In addition to treating myasthenia gravis, pyridostigmine is used to reverse neuromuscular blocks, relieve symptoms in congenital myasthenic syndromes, and protect against certain nerve
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersInternational brands: Kalymin N