Calcium chloride is an ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate. It is highly soluble in water and it is deliquescent.
- Mechanism
- Curator reviewed
Calcium chloride in water dissociates to provide calcium (Ca2+) and chloride (Cl-) ions. They are normal constituents of the body fluids and are dependent on various physiological mechanisms for maintenance of balance between intake and output. For hyperkalemia, the influx of calcium helps restore the normal gradient between threshold potential and resting membrane potential.
- Primary indication
- For the treatment of hypocalcemia in those conditions requiring a prompt increase in blood plasma calcium levels, for the treatment of magnesium intoxication due to overdosage of magnesium sulfate, and used to combat the deleterious...Curator reviewed · 42 structured indications
- Formula / weight
- CaCl2 · 110.984 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1969
- Also known as
- calcium(2+) chloride
- Code names
- E-509 · INS-509 · INS NO.509
- Brand names
Resolves to
UXVMQQNJUSDDNG-UHFFFAOYSA-LSMILES[Cl-].[Cl-].[Ca++]What you can answer from here — as of September 29, 2026
Which drugs share a target with Calcium chloride, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account