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Potassium cation
go.drugbank.com/drugs/DB01345ApprovedThe cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge. … The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.
Synonyms: potassium(1+), potassium(1+) ionMixtures: Telom-X-geneGlecaprevir
go.drugbank.com/drugs/DB13879ApprovedInvestigationalMavyret is also indicated for HCV genotype 1-infected patients who have been previously treated with regimens either containing an NS5A inhibitor or an NS3/4A protease inhibitor, but not both [L940]. … In clinical trials, this combination therapy achieved SVR12 rate, or undetectable Hepatitis C for twelve or more weeks after the end of treatment, of ≥93% across genotypes 1a, 2a, 3a, 4, 5 and 6 [L41080
Mixtures: MAVIRET® 100/40 MG TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, P-glycoprotein substratesDroxidopa
go.drugbank.com/drugs/DB06262ApprovedInvestigationalThere is a deficit of noradrenaline as well as of dopamine in Parkinson's disease and it has been proposed that this underlies the sudden transient freezing seen usually in advanced disease. … Though L-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in clinical trials at the phase III point in the United States (U.S.), Canada, Australia, and throughout
Synonyms: L-DOPS, L-DihydroxyphenylserineCategories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor AgonistsXylose
go.drugbank.com/drugs/DB09419ApprovedWithdrawnD-Xylose is a sugar widely used as a diabetic sweetener in food and beverage. Xylose has also been used as a diagnostic agent to observe malabsorption. … Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood.
Synonyms: D-Xylose, aldehydo-D-xyloseEstriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedA hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes.
Mixtures: GYNOFLOR 50 MG/0.03 MG VAJÄ°NAL TABLET, 6 ADETCategories: P-glycoprotein inducers, P-glycoprotein substratesAmikacin
go.drugbank.com/drugs/DB00479ApprovedInvestigationalVet approved[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. … Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.
Synonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A, D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)-Categories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … [L4779] It was also approved by the European Commission on January 7, 2021.[L45241]
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: XOFLUZA 20 MG FÄ°LM KAPLI TABLET, 2 ADET, XOFLUZA 20 MG FÄ°LM KAPLI TABLET, 4 ADETMetaxalone
go.drugbank.com/drugs/DB00660ApprovedInvestigationalMetaxalone is associated with few side effects and is available as a 800 mg scored tablet. … Metaxalone is a moderate to strong muscle relaxant used in the symptomatic treatment of musculoskeletal pain caused by strains, sprains, and other musculoskeletal conditions.
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Heterocyclic Compounds, 1-RingAdapalene
go.drugbank.com/drugs/DB00210ApprovedInvestigationalOn December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel.[L12873] … [A193518] Differin®, produced by Galderma Labs, was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution.
Synonyms: 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acidMixtures: GLENPALENE-C® GEL, Clindap-TVitamin E
go.drugbank.com/drugs/DB00163ApprovedInvestigationalNutraceuticalVet approvedVitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active[A176104]. … Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA[FDA Label].
Synonyms: (2R,4'R,8'R)-α-tocopherol, (R,R,R)-α-tocopherolInternational brands: Aquasol E, Amino-Opti-E