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Displaying results 1431 - 1440 of 10000 in total
  1. Drug

    Chloric acid

    go.drugbank.com/drugs/DB14150
    Approved

    Categories: Compounds used in a research, industrial, or household settingProducts: Aquacid-200, Aquacid-220
  2. Drug

    Flumethasone

    go.drugbank.com/drugs/DB00663
    ApprovedVet approved

    As it is a privalate salt, its anti-inflammatory action is concentrated at the site of application. … This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.

    Mixtures: LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 15 G, LOCACORTENE VİOFORME 0,2 MG/G+30 MG/G KREM, 30 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.

    Categories: Prostaglandins ISynonyms: Prostaglandin X, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid
  4. Drug

    Upadacitinib

    go.drugbank.com/drugs/DB15091
    ApprovedInvestigational

    Upadacitinib is an oral Janus kinase (JAK)1-selective inhibitor and a disease-modifying antirheumatic drug (DMARD) used in the treatment of rheumatoid arthritis to slow down disease progression. … Rheumatoid arthritis is a chronic autoimmune inflammatory disease affecting the peripheral joints.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: RİNVOQ 15 MG UZATILMIŞ SALIMLI TABLET, 98 ADET, Rinvoq 45 mg Uzatılmış Salımlı Tablet, 28 ADET
  5. Drug

    Carfilzomib

    go.drugbank.com/drugs/DB08889
    ApprovedInvestigational

    Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: ANPROTSOM ® 60 MG, Kyprolis 10 mg IV İnfüzyonluk Çözelti Hazırlamak İçin Toz, 1 ADET
  6. Drug

    Rilmenidine

    go.drugbank.com/drugs/DB11738
    ApprovedWithdrawn

    Rilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.

    Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsProducts: Iterium 1 mg - Tabletten, HYPERIUM 1 MG TABLET, 30 ADET
  7. Drug

    Tafluprost

    go.drugbank.com/drugs/DB08819
    Approved

    Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

    Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: SAFLUTAN®, SAFLUTAN 15 MCG/ML TEK DOZLUK GOZ DAMLASI, 30 ADET
  8. Drug

    Vericiguat

    go.drugbank.com/drugs/DB15456
    ApprovedInvestigational

    [A227458,A227488] Cyclic GMP acts as a second messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and these diverse cellular effects have implicated … [L31178] Vericiguat was approved by the FDA in January 2021 - developed by Merck under the brand name Verquvo - for use in certain patients with systolic heart failure.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingProducts: VERQUVO 5 MG FİLM KAPLI TABLET , 14 ADET, VERQUVO 5 MG FİLM KAPLI TABLET , 28 ADET
  9. Drug

    Bedaquiline

    go.drugbank.com/drugs/DB08903
    ApprovedInvestigational

    Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. … [L48506] Although the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB

    Synonyms: 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-olCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  10. Drug

    Ixabepilone

    go.drugbank.com/drugs/DB04845
    ApprovedInvestigational

    Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug. … Ixabepilone is a semisynthetic analogue of epothilone B. It has a lactone–lactam modification that minimizes susceptibility to esterase degradation.

    Synonyms: Azaepothilone B, Aza-epothilone BCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates