Search
Pidolic acid
go.drugbank.com/drugs/DB03088ApprovedInvestigationalPidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics … There are currently little to no medicines available that are clinically approved or marketed for employing pidolic acid as an active ingredient for any particular formal indication.
Carbopol 974P
go.drugbank.com/drugs/DB05384ApprovedWithdrawnThe compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued. … It was under development by ReProtect LLC. It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.
Zinc acetate
go.drugbank.com/drugs/DB14487ApprovedInvestigationalMixtures: Benadryl Bug Bite Relief, Children's Benadryl Bug Bite ReliefLevorphanol
go.drugbank.com/drugs/DB00854ApprovedIt is nearly as effective orally as by injection.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeMebanazine
go.drugbank.com/drugs/DB09248ApprovedWithdrawnIt was used in the past as an antidepressant in the 1960s, but has since been discontinued because of its hepatotoxic potential. … Mebanazine, also known as _Actomol_, is a monoamine oxidase inhibitor (MAOI) belonging to the _hydrazine_ class of chemicals.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeHydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigational[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. … Historically, hydrocodone has been used as a cough suppressant although this has largely been replaced by [dextromethorphan] in current cough and cold formulations.
Mixtures: Co-gesicCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeQuizartinib
go.drugbank.com/drugs/DB12874ApprovedInvestigational[A260641] Quizartinib was approved by the FDA in July 2023 and developed under the brand name VANFLYTA by Daiichi Sankyo. … [A260651] Therefore, quizartinib is proven to be a beneficial addition to the current AML treatment regimen, although serious side effects such as QT prolongation necessitates further research to optimize
Cefmenoxime
go.drugbank.com/drugs/DB00267ApprovedIt is reported to exhibit high activity against a wide variety of gram-positive and gram-negative bacteria.
Icotrokinra
go.drugbank.com/drugs/DB21724ApprovedInvestigational[L56108,L56118] Icotrokinra was approved by the US FDA in March 2026 for the systemic treatment of moderate-to-severe plaque psoriasis.[L56108] … It was jointly discovered and developed by Protagonist and Johnson & Johnson[L56118] and provides a novel, oral treatment option for patients requiring systemic therapy for plaque psoriasis.
Bimekizumab
go.drugbank.com/drugs/DB12917ApprovedInvestigationalof moderate-to-severe psoriasis,[A244450,A244455] likely owing to its dual inhibition of both IL-17A and IL-17F. … [L39665,L39680] It is the first IL-17 inhibitor to target both IL-17A and IL-17F.