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SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2
go.drugbank.com/bio_entities/BE0013298TargetHumansThe transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. … Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner
Polypeptides: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2Angiotensin II
go.drugbank.com/drugs/DB11842ApprovedInvestigationalAs distributive shock is the most common type of shock in the inpatient setting and affects up to one third of patients in the intensive care unit, the FDA determined that there is a need for treatment … As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's Giapreza (angiotensin II) Injection for Intravenouse Infusion for the indication of acting as a vasoconstrictor to increase blood pressure
Synonyms: 5-L-isoleucineangiotensin II, 5-isoleucine-angiotensin IISalts: Angiotensin II acetateGVAX
go.drugbank.com/drugs/DB17276InvestigationalGVAX is a granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-transfected tumor cell vaccine.
Synonyms: Replication-incompetent GM-CSF-expressing gene-modified allogeneic pancreatic cancer cell lines, Replication-incompetent GM-CSF-expressing gene-modified allogeneic acute myeloid leukemia cancer cell linesAmifostine
go.drugbank.com/drugs/DB01143ApprovedInvestigationalA phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Categories: Compounds used in a research, industrial, or household settingProducts: ETHYOL 500 MG IV INFUZYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADET, Ethyol - Pws IV 500mg/vialSodium tetradecyl sulfate
go.drugbank.com/drugs/DB00464ApprovedAn anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 7-Ethyl-2-methyl-4-undecanol sulfate sodium salt, Sodium 2-methyl-7-ethylundecanol-4-sulfateSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
go.drugbank.com/bio_entities/BE0010396TargetHumansBinds to RNA in a promiscuous manner (By similarity). In brown adipose tissue, involved in the regulation of thermogenic genes expression (By similarity) … In resting neurons, transcription of the c-FOS promoter is inhibited by SMARCA4-dependent recruitment of a phospho-RB1-HDAC repressor complex.
Polypeptides: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4Activated charcoal
go.drugbank.com/drugs/DB09278ApprovedInvestigationalIt works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. … It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances
Mixtures: FINIGAX®, FINIGAX® CAPSULASCategories: Compounds used in a research, industrial, or household settingInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalIf left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … These biochemical changes result in a reduced tendency for self-association resulting in dissolution to a dimer and then to a monomer that is absorbed more rapidly after subcutaneous injection compared
Mixtures: HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml, HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/mlCategories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersLincomycin
go.drugbank.com/drugs/DB01627ApprovedInvestigationalVet approvedLincomycin is a lincosamide antibiotic first isolated from the soil bacterium _Streptomyces lincolnensis_ in Lincoln, Nebraska. … in use.
Categories: Heterocyclic Compounds, 1-RingProducts: LINCOCIN 600 MG IM/IV AMPUL, 1 ADET, LINCOCIN 2 ML 600 MG 1 AMPULIbuprofen
go.drugbank.com/drugs/DB01050ApprovedInvestigational[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin. … [A39076] On the available products, ibuprofen is administered as a racemic mixture.
Synonyms: (±)-α-methyl-4-(2-methylpropyl)benzeneacetic acid, (±)-2-(p-isobutylphenyl)propionic acidInternational brands: Act-3, Alges-X