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Displaying results 1451 - 1460 of 10000 in total
  1. Drug

    Efatutazone

    go.drugbank.com/drugs/DB11894
    Investigational

    Efatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    2,4-thiazolidinedione

    go.drugbank.com/drugs/DB11898
    Investigational

    Thiazolidinedione has been investigated for the treatment of Type 2 Diabetes, Diabetes Mellitus, and DIABETES MELLITUS, TYPE 2.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Timapiprant

    go.drugbank.com/drugs/DB11900
    Investigational

    OC000459 is under investigation for the treatment of Severe Eosinophilic Asthma. OC000459 has been investigated for the treatment of Bronchial Asthma.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Apalutamide

    go.drugbank.com/drugs/DB11901
    ApprovedInvestigational

    In a randomized trial, the median metastasis-free survival for patients taking apalutamide was 40.5 months compared to 16.2 months for patients taking a placebo [L1295]. … In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846].

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MG
  5. Drug

    Rociletinib

    go.drugbank.com/drugs/DB11907
    Investigational

    Rociletinib has been used in trials studying the treatment and prevention of Nonsmall Cell Lung Cancer, Non-small Cell Lung Cancer, and Locally Advanced or Metastatic Non-small Cell Lung Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Lebrikizumab

    go.drugbank.com/drugs/DB11914
    ApprovedInvestigational

    This approval is based on the positive results obtained from the Phase 3 studies ADvocate 1 and ADvocate 2, where nearly 80% of patients taking lebrikizumab either as monotherapy or combination therapy … Lebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate.[L51374] It binds to a different epitope compared [tralokinumab].

  7. Drug

    Guadecitabine

    go.drugbank.com/drugs/DB11918
    Investigational

    Guadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    6-O-benzylguanine

    go.drugbank.com/drugs/DB11919
    Investigational

    6-O-benzylguanine has been used in trials studying the treatment of HIV Infection, Adult Gliosarcoma, Adult Glioblastoma, Stage I Adult Hodgkin Lymphoma, and Stage II Adult Hodgkin Lymphoma, among others

    Synonyms: O(6)-BenzylguanineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  9. Drug

    Lesogaberan

    go.drugbank.com/drugs/DB11920
    Investigational

    Lesogaberan has been used in trials studying the treatment and basic science of GERD, Reflux, Heartburn, Regurgitation, and Reflux Disease, among others.

    Categories: GABA-A Receptor Agonists
  10. Drug

    Epelsiban

    go.drugbank.com/drugs/DB11934
    Investigational

    Epelsiban has been investigated for the treatment of Premature Ejaculation.

    Categories: Heterocyclic Compounds, 1-Ring