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Displaying results 1451 - 1460 of 10000 in total
  1. Drug

    Cadisegliatin

    go.drugbank.com/drugs/DB18886
    Investigational

    Cadisegliatin is under investigation in clinical trial NCT06334133 (Cadisegliatin as Adjunctive Therapy in Type 1 Diabetes).

    Synonyms: 2-((2-(3-cyclohexyl-3-((1r,4r)-4-propoxycyclohexyl)ureido)thiazol-5-yl)thio)acetic acid, [(2-{[cyclohexyl(trans-4-propoxycyclohexyl)carbamoyl]amino}-1,3-thiazol-5-yl)sulfanyl]acetic acid
  2. Drug

    Hexachlorophene

    go.drugbank.com/drugs/DB00756
    ApprovedWithdrawn

    It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797) … A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms.

    Synonyms: 2,2'-dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane, bis(2-hydroxy-3,5,6-trichlorophenyl)methaneInternational brands: E-Z scrub, Surgi-Cen
  3. Drug

    CC-90001

    go.drugbank.com/drugs/DB18445
    Investigational

    Synonyms: 2-(TERT-BUTYLAMINO)-4-((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYLAMINO)-PYRIMIDINE-5-CARBOXAMIDE, 2-((1,1-DIMETHYLETHYL)AMINO)-4-(((1R,3R,4R)-3-HYDROXY-4-METHYLCYCLOHEXYL)AMINO)-5-PYRIMIDINECARBOXAMIDECategories: MATE 1 Inhibitors, MATE 2 Inhibitors
  4. Drug

    APPD

    go.drugbank.com/drugs/DB18603
    Experimental

    Synonyms: D-GLYCERO-.ALPHA.-L-TALO-HEPTOFURANURONAMIDE, 5-O-(5-AMINO-5-DEOXY-.BETA., -D-RIBOFURANOSYL)-1,6-DIDEOXY-1-(3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINYL)-6-((4-OXO-4-(((4-(4-(4-(TRIFLUOROMETHOXY)PHENOXY)-1-PIPERIDINYL)PHENYL)METHYL)AMINO)BUTYL)AMINO)-Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Bambuterol

    go.drugbank.com/drugs/DB01408
    Investigational

    Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.

    Categories: Adrenergic beta-2 Receptor Agonists, Selective Beta 2-adrenergic AgonistsSynonyms: (±)-5-(2-(tert-butylamino)-1-hydroxyethyl)-m-phenylene bis(dimethylcarbamate)
  6. Drug

    Tebapivat

    go.drugbank.com/drugs/DB19338
    Investigational

    Tebapivat is under investigation in clinical trial NCT05490446 (A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-risk Myelodysplastic Syndromes (LR-MDS)).

    Synonyms: 6-[(6-aminopyridin-2-yl)methyl]-4-methyl-2-[(1H-pyrazol-3-yl)methyl]-4,6-dihydro-5H-[1,3]thiazolo[5',4':4,5]pyrrolo[2,3-d]pyridazin-5-one
  7. Drug

    Sonrotoclax

    go.drugbank.com/drugs/DB18753
    ApprovedInvestigational

    Sonrotoclax is a selective, potent, small-molecule inhibitor of BCL-2, an antiapoptotic protein overexpressed in B-cell malignancies. … [L56193,A275521] Sonrotoclax was rationally designed as a BH3 mimetic with a shallow and broad interaction with the P2 pocket of BCL-2, achieved through a novel 7-azaspiro[3.5]nonane linker; this binding

    Synonyms: N-[4-({[(1r,4r)-4-hydroxy-4-methylcyclohexyl]methyl}amino)-3- nitrobenzene-1-sulfonyl]-4-(2-{(2S)-2-[2-(propan-2-yl)phenyl]pyrrolidin- 1-yl}-7-azaspiro[3.5]nonan-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-5- ylCategories: BCL-2 Inhibitor, P-glycoprotein substrates
  8. Drug

    Brodimoprim

    go.drugbank.com/drugs/DB13795
    Experimental

    Synonyms: 2,4-diamino-5-(4-bromo-3,5-dimethoxybenzyl)pyrimidineCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Imino[2-(2-oxo-1,2-dihydro-3-pyridinyl)-1H-benzimidazol-5-yl]methanaminium

    go.drugbank.com/drugs/DB04442
    Experimental

  10. Drug

    2-Acetyl-3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt P,P'-Dioxide

    go.drugbank.com/drugs/DB02410
    Experimental

    Synonyms: 2-Acetyl-3-[(4-Amino-2-Methyl-5-Pyrimidinyl)Methyl]-4-Methyl-5-(4,6,6-Trihydroxy-3,5-Dioxa-4,6-Diphosphahex-1-Yl)Thiazolium Inner Salt P,P'-Dioxide