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Displaying results 1461 - 1470 of 10000 in total
  1. Drug

    Rituximab

    go.drugbank.com/drugs/DB00073
    ApprovedInvestigational

    Rituximab is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. … On November 28, 2018, the US FDA approved _Truxima_, the first biosimilar to Rituxan (Rituximab) [L4808].

    Categories: CD20 (Clusters of Differentiation 20) inhibitorsProducts: MABTHERA SOLUCION PARA INFUSION 10 MG/ML, MABTHERA ROCHE SOLUCION PARA INFUSION 10 MG/ML
  2. Drug

    Alogliptin

    go.drugbank.com/drugs/DB06203
    ApprovedInvestigational

    Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). … It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.

    Mixtures: OSENI 25 MG/15 MG TABLETS, OSENI 25 MG/15 MG TABLETSProducts: NESINA TABLET 25 MG, NESINA TABLET 6.25 MG
  3. Drug

    Doxepin

    go.drugbank.com/drugs/DB01142
    ApprovedInvestigational

    [T83] In a strict sense, doxepin is not a tricyclic antidepressant but it is commonly associated with the class since it shares a lot of properties with members of the drug family including [amitriptyline … [L5971] However, in 2010 it was approved for the treatment of insomnia. The latter indication was presented by Pernix Therapeutics.[L5974]

    Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: EXPAN® 50 MG, Rho-doxepin-10 Mg Cap
  4. Drug

    Burosumab

    go.drugbank.com/drugs/DB14012
    ApprovedInvestigational

    X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. … Most children with XLH suffer from bowed or bent legs, short stature, bone pain and severe dental pain.

    Categories: Drugs for Treatment of Bone DiseasesProducts: CRYSVITA 10 MG SOLUTION FOR INJECTION, CRYSVITA 20 MG SOLUTION FOR INJECTION
  5. Drug

    Frovatriptan

    go.drugbank.com/drugs/DB00998
    Approved

    Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. … Frovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: FROVATRIPTAN EG, NEWART 2.5 MG TABLET, 12 ADET
  6. Drug

    Sodium phosphate, dibasic

    go.drugbank.com/drugs/DB14502
    ApprovedInvestigational

    Mixtures: ENEMA 161 MG/ML+59 MG/ML REKTAL ÇÖZELTİ, 135 ML, ENEMA 161 MG/ML+59 MG/ML REKTAL ÇÖZELTİ, 210 ML
  7. Drug

    Eravacycline

    go.drugbank.com/drugs/DB12329
    ApprovedInvestigational

    of anaerobic pathogens [A38683]. … It was first approved by the FDA on August 27, 2018 [L4540].

    Categories: combinations of tetracyclines
  8. Target

    Sodium-coupled neutral amino acid transporter 3

    go.drugbank.com/bio_entities/BE0000285
    TargetTransporterHumans

    Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity (PubMed:10823827). Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from a...

    Synonyms: SN1
  9. Drug

    Propyliodone

    go.drugbank.com/drugs/DB09366
    Approved

    Radiopaque medium usually in oil; used in bronchography.

    Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household setting
  10. Drug

    Nonivamide

    go.drugbank.com/drugs/DB11324
    Approved

    The structures of [DB06774] and nonivamide differ only slightly with respect to the fatty acid moiety of the side chain (8-methyl nonenoic acid versus nonanoic acid) [F31]. … This drug has been studied in combination with Nicarboxil in the treatment of lower back pain [L2642].

    Mixtures: Nonivamid + Nicoboxil Zentiva 4 mg/g + 25 mg/g Salbe