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Etoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnLike any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2) to reduce the generation of prostaglandins (PGs) from arachidonic acid. … It is approved in more than 60 countries worldwide but not in the US.
Mixtures: ETRAL - TRChikungunya vaccine (live, attenuated)
go.drugbank.com/drugs/DB18701ApprovedInvestigational[L48726] It is approved for use in patients 18 years of age and older who are at high-risk of exposure to chikungunya virus. … In late 2013, the first cases were identified in the Caribbean, and it has since spread to most of the Americas.[L48786] There are no approved treatments for active chikungunya virus infection.
Hexaminolevulinate
go.drugbank.com/drugs/DB06261ApprovedInvestigationalIn solution form it is instilled intravesically for use with photodynamic blue light cystoscopy as an adjunct to white light cystoscopy. On May 28, 2010, the U.S. … use in combination with the Karl Storz Photodynamic Diagnostic D-Light C (PDD) System for cystoscopic detection of non-muscle invasive papillary cancer of the bladder for patients suspected or known to
Proline
go.drugbank.com/drugs/DB00172ApprovedInvestigationalNutraceuticalProline is a non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons.
Mixtures: Vamin N, AMINOSTERIL N-HEPA 8%Potassium alum
go.drugbank.com/drugs/DB09087ApprovedWithdrawnPotassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance. … [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O).
Mixtures: Gingicord W Epineph and Alum Size No 1, Gingicord W Epineph and Alum Size No 3Ivabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalRecently a new indication was added to treat symptomatic heart failure from dilated cardiomyopathy for patients 6 months or more in age[Label]. … Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the
Cefoxitin
go.drugbank.com/drugs/DB01331ApprovedInvestigationalIt is derived from cephamycin C, which is produced by <i>Streptomyces lactamdurans</i>.
Mavorixafor
go.drugbank.com/drugs/DB05501ApprovedInvestigational[L50647] WHIM syndrome is caused by mutations in the _CXCR4_ gene, which leads to overactivation of CXCR4 signalling pathways.[A263652] Mavorixafor prevents the activation of CXCR4. … by a reduced number of mature neutrophils and lymphocytes.
Synonyms: 1,4-BUTANEDIAMINE, N-(1H-BENZIMIDAZOL-2-YLMETHYL)-N-((8S)-5,6,7,8-TETRAHYDRO-8-QUINOLINYL)-, 1,4-BUTANEDIAMINE, N1-(1H-BENZIMIDAZOL-2-YLMETHYL)-N1-((8S)-5,6,7,8-TETRAHYDRO-8-QUINOLINYL)-Ticlopidine
go.drugbank.com/drugs/DB00208ApprovedIt is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. … The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they
Insulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalcells that the body is no longer able to produce insulin on its own. … Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal muscle.