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Bexagliflozin
go.drugbank.com/drugs/DB12236ApprovedInvestigationalBexagliflozin is a highly specific and potent sodium-glucose co-transporter 2 (SGLT2) inhibitor. … [A256408,A256413,L44758] Similar to other SGLT2 inhibitors, bexagliflozin contains three basic moieties: glucose, two benzene rings and a methylene bridge.
Categories: Drugs Used in DiabetesMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalIt also has a number of unique characteristics that have led to its increased use in the last two decades; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids … Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersMucor racemosus
go.drugbank.com/drugs/DB10808ApprovedMucor racemosus is a fungus which can provoke allergic reactions. Mucor racemosus extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureInfluenza B virus B/Washington/02/2019 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB15620ApprovedInvestigationalInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses.
Mixtures: VaxigripTetra Injektionssuspension in einer Fertigspritze, Influvac Tetra Injektionssuspension in einer FertigspritzeFenfluramine
go.drugbank.com/drugs/DB00574ApprovedIllicitInvestigationalWithdrawn[A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as an appetite suppressant until concerns regarding cardiotoxicity in obese patients lead to its withdrawal … [A214688, A214691, A214700] Fenfluramine was granted initial FDA approval in 1973 prior to its withdrawal; it was granted a new FDA approval on June 25, 2020, for treatment of patients with Dravet syndrome
International brands: Ponderax PACytochrome c1, heme protein, mitochondrial
go.drugbank.com/bio_entities/BE0003854TargetHumansThe respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c
Synonyms: Complex III subunit 4, Complex III subunit IVPenicillium expansum
go.drugbank.com/drugs/DB10810ApprovedPenicillium expansum is a fungus which can provoke allergic reactions. Penicillium expansum extract is used in allergenic testing.
Mixtures: Number Ten Mold Mixture, Number Ten Mold MixtureCytochrome b
go.drugbank.com/bio_entities/BE0000938TargetHumansComponent of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. … The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis
Synonyms: Complex III subunit 3, Complex III subunit IIIAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009. … Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with
Lindane
go.drugbank.com/drugs/DB00431ApprovedWithdrawnAn organochlorine insecticide that has been used as a pediculicide and a scabicide. … In Canada, Lindane is not recommmended as a first-line therapy due to reports of resistance, neurotoxicity, and bone marrow suppression, but has been approved by the FDA as a second-line therapy for topical
Categories: Compounds used in a research, industrial, or household setting