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Umeclidinium
go.drugbank.com/drugs/DB09076ApprovedInvestigational[L47042] Later, it was further approved as a combination product with [vilanterol] and [vilanterol]/[fluticasone furoate] under the brand name ANORO ELLIPTA and TRELEGY ELLIPTA respectively. … [A7719] However, even though umeclidinium monotherapy is well-tolerated for up to 14 days, it is more likely to be used in combination therapy, as the international Gold Initiative for Chronic Obstructive
Iopodic acid
go.drugbank.com/drugs/DB09333ApprovedWithdrawnThis drug was approved on March 15, 1962 but it is nowadays discontinued from the FDA and Health Canada. … [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque property. It was developed and filed to the FDA by the company BRACCO.
Denileukin diftitox
go.drugbank.com/drugs/DB00004ApprovedInvestigational[A264344] In 2014, it was withdrawn voluntarily from the market due to manufacturing issues; however, the biologics license application (BLA) for denileukin diftitox was resubmitted, and it was approved … [A264349, L51254] Denileukin diftitox was originally approved by the FDA in 1999 for the treatment of cutaneous T-cell lymphoma (CTCL),[A264339, L51264] making it the first fusion protein cytotoxin
Synonyms: N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2Tagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigational[A253762] It was also approved by the European Commission on January 7, 2021.[L43712] … It is a fusion protein composed of a human interleukin-3 (IL-3) that is genetically fused to the catalytic and translocation domains of truncated diphtheria toxin (DT) produced in _Escherichia coli_.
Homosalate
go.drugbank.com/drugs/DB11064ApprovedIt is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. … It is a common ingredient in many commercially available sunscreens. There are no reported adverse effects from homosalate.
Mixtures: VITAMIN E MOISTURE-PROTECT SPF 30 PA plus plus plus, Essence Light Sunscreen SPF 50 PaPramocaine
go.drugbank.com/drugs/DB09345ApprovedPramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic. … It works by preventing ionic fluctuations needed for neuron membrane depolarization and action potential propagation.
Mixtures: Itch Relief Medicated Pads CVS, First Aid Clear Anti-Itch medicated pads Rite AidCategories: Antihistamines, Anesthetics, Etc.Nitrogen
go.drugbank.com/drugs/DB09152ApprovedInvestigationalVet approvedAt room temperature, it is a transparent, odorless diatomic gas. Liquid nitrogen is used principally in cryotherapy for removal of diseased skin.
Mixtures: Compressed Gas N.O.S., Lung Diffusion Test Mixture GasProducts: Nitrogen Gas 99%, Stickstoff medizinisch Linde - Gas zur medizinischen Anwendungalpha-Tocopherol succinate
go.drugbank.com/drugs/DB14001ApprovedNutraceuticalVet approvedNevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. … Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.
Mixtures: Children Choice Multivitamin W Iron Chew Tab, Hyper E TabCategories: Vitamin ESodium lauryl sulfate
go.drugbank.com/drugs/DB00815ApprovedIt is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity. … It usually consists of a mixture of sodium alkyl sulfates, mainly the lauryl.
Defibrotide
go.drugbank.com/drugs/DB04932ApprovedInvestigationalIt is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. In the USA it is was approved in March, 2016 as Defitelio. … It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects).