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Stannous fluoride
go.drugbank.com/drugs/DB11092ApprovedInvestigationalStannous Fluoride, or Tn(II) Fluoride, is a compound commonly used in toothpastes for the prevention of gingivitis, dental infections, cavities, and to relieve dental hypersensitivity. … Although similar in function and activity to Sodium Fluoride (NaF), the conventionally added ingredient in toothpastes, stannous fluoride has been shown to be more effective at stopping and reversing dental
Categories: Compounds used in a research, industrial, or household settingProducts: H E B Restore and Defend, Ionite HCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin Receptor AntagonistsProducts: Q-citalopram, M-citalopramLasmiditan
go.drugbank.com/drugs/DB11732ApprovedInvestigational[A187316] Triptans abort migraines via action at several serotonin receptors, including 5-HT<sub>1D</sub> and 5-HT<sub>1B</sub> receptors, and activity at the 5-HT<sub>1B</sub> receptor has been specifically … [sumatriptan]) have seen preferential use in the acute treatment of migraines due to their relatively favourable efficacy and safety.
Categories: Serotonin (5-HT) 1F Receptor Agonists, MATE 1 InhibitorsProducts: 1 RayvowVitamin A
go.drugbank.com/drugs/DB00162ApprovedInvestigationalNutraceuticalVet approvedDietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.
Synonyms: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol, Vitamin A AlcoholInternational brands: Chocola ABenznidazole
go.drugbank.com/drugs/DB11989ApprovedInvestigationalBenznidazole was granted accelerated approval for the treatment of Chagas disease in children 2-12 years of age by the FDA on August 29, 2017.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: ABALEA ®100 MGAtovaquone
go.drugbank.com/drugs/DB01117ApprovedInvestigationalAtovaquone is a hydroxynaphthoquinone, or an analog of ubiquinone, that has antimicrobial and antipneumocystis activity. It is being used in antimalarial protocols.
Synonyms: 2-(trans-4-(p-Chlorophenyl)cyclohexyl)-3-hydroxy-1,4-naphthoquinoneMixtures: ATOVAQUONE E PROGUANILE SANDOZ, ATOVAQUONE E PROGUANILE MYLAN GENERICSEfonidipine
go.drugbank.com/drugs/DB09235InvestigationalThe drug has been shown to block T-type in addition to L-type calcium channels [A7844, A32001]. It has also been studied in atherosclerosis and acute renal failure [A32001]. … This drug is also known as NZ-105, and several studies have been done on its pharmacokinetics in animals [L1456].
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingBrigatinib
go.drugbank.com/drugs/DB12267ApprovedInvestigational[A31311] It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a pivotal player in the transformation of susceptible lung parenchyma. … Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR).
Mixtures: ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG, ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MGCategories: Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index, MATE 1 InhibitorsGlatiramer
go.drugbank.com/drugs/DB05259ApprovedInvestigationalGlatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. … [A248870] Originally, glatiramer acetate was designed as a stimulant of myelin basic protein (MBP), a myelin antigen involved in the development of multiple sclerosis (MS), to induce experimental autoimmune
Synonyms: (T,G)-A-L, COP 1Products: AUTIX®, COPAXONE®Inosine
go.drugbank.com/drugs/DB04335ApprovedA purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 9-β-D-ribofuranosyl-9H-purin-6-ol, 9-β-D-ribofuranosylhypoxanthine