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Displaying results 1471 - 1480 of 10000 in total
  1. Target

    Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

    go.drugbank.com/bio_entities/BE0003558
    TargetHumans

    Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (PubMed:10725373, PubMed:10906126, PubMed:11050148) … Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP (PubMed:10725373, PubMed:10906126, PubMed:11050148, PubMed:16330539).

    Polypeptides: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11ASynonyms: cAMP and cGMP phosphodiesterase 11A
  2. Target

    Ankyrin repeat and protein kinase domain-containing protein 1

    go.drugbank.com/bio_entities/BE0009411
    TargetHumans

    Polypeptides: Ankyrin repeat and protein kinase domain-containing protein 1
  3. Drug

    Physostigmine

    go.drugbank.com/drugs/DB00981
    Approved

    It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity. … It can be applied topically to the conjunctiva.

    Categories: Antiglaucoma Preparations and MioticsProducts: Antilirium Inj 1mg/ml
  4. Indication

    Refractory Chemotherapy-Induced Nausea and Vomiting (CINV)

    go.drugbank.com/conditions/DBCOND0142498
    Drugs: Nabilone
    Synonyms: Refractory Chemotherapy-Induced Nausea and Vomiting (CINV)
  5. Drug

    Digitoxin

    go.drugbank.com/drugs/DB01396
    ApprovedWithdrawn

    It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)

    Products: DIGITOXIN AWD 0.07MG
  6. Drug

    5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB07140
    Experimental

    Synonyms: 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  7. Drug

    DL-alpha-Tocopherol

    go.drugbank.com/drugs/DB14476
    ApprovedInvestigational

    Mixtures: VITALIPID N ADULT, 10ML GLASS AMPOULE, Eden With Vitamins A, C, and EProducts: Advanced E With Non-medicinal Grape Seed Extract
  8. Drug

    Muromonab

    go.drugbank.com/drugs/DB00075
    ApprovedInvestigationalWithdrawn

    Murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. … More specifically it is a purified murine (mouse) monoclonal antibody, directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes) cultured using the murine ascites method.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: Orthoclone Okt 3 Sterile Solution IV 1mg/ml
  9. Drug

    Iron polymaltose

    go.drugbank.com/drugs/DB15763
    ApprovedInvestigationalWithdrawn

    Mixtures: SANTAFER FORT 100MG/0,35 MG FILM KAPLI TABLET, 30 ADETProducts: MALTOFER FILM-COATED TABLETS 100MG, SANTAFER 100MG/2ML AMPUL, 5 ADET
  10. Drug

    Polidocanol

    go.drugbank.com/drugs/DB06811
    ApprovedInvestigational

    The formula for Polidocanol has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization (n) of approximately 9 and a mean molecular weight of approximately 600. … It is marketed under the brand names Asclera and Varithena.

    Products: VARITHENA POLIDOCANOL INJECTABLE FOAM 10MG/ML