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Digoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. … [L9143] This drug originates from the foxglove plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and botanist in the 1780s.
Categories: Compounds used in a research, industrial, or household settingProducts: LANOXIN TABLET 0.25 mg, LANOXIN INJECTION 0.5 mg/2 mlAcamprosate
go.drugbank.com/drugs/DB00659ApprovedInvestigationalIt was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA).
Synonyms: N-Acetylhomotaurine, N-acetyl homotaurineCategories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependenceTafenoquine
go.drugbank.com/drugs/DB06608ApprovedInvestigational[A35677] It was FDA approved on July 20, 2018.[L3770] … [A35671, A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a substitute for primaquine that would be more effective against relapsing vivax malaria.
Probucol
go.drugbank.com/drugs/DB01599ApprovedInvestigationalWithdrawnA drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Categories: Compounds used in a research, industrial, or household settingPotassium hydroxide
go.drugbank.com/drugs/DB11153ApprovedRecently, it has been studied for efficacy and tolerability in the treatment of warts. … Also commonly referred to as _caustic potash_, it is a potent base that is marketed in several forms including pellets, flakes, and powders.
Mixtures: Vamin N, NUTRIFLEX PERI IN 2000ML TWIN-FLEXCategories: Compounds used in a research, industrial, or household settingAttapulgite
go.drugbank.com/drugs/DB01574ApprovedVet approvedWithdrawnWhen used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. … Until 2003, it was the active ingredient used in Kaopectate, before that product was reformulated with bismuth subsalicylate.
Categories: Compounds used in a research, industrial, or household settingFenofibric acid
go.drugbank.com/drugs/DB13873ApprovedInvestigationalFenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. … It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.
Mixtures: FENOVAS®20 MG, FENOVAS®10 MGProducts: TRILIPIX 135 MG, ACIDO FENOFIBRICO 135 MGFluciclovine (18F)
go.drugbank.com/drugs/DB13146ApprovedInvestigationalIt presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. … [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the body.
Lutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985ApprovedInvestigationalPatients with GEP-NETs have limited second-line treatment options after the metastasis of tumors and inadequate therapeutic response from first-line therapies. … In a clinical trial involving patients with advanced somatostatin receptor-positive GEP-NET, the treatment of Lutetium Lu 177 dotatate in combination with octreotide resulted in longer progression-free
Categories: Compounds used in a research, industrial, or household settingBrexanolone
go.drugbank.com/drugs/DB11859ApprovedInvestigationalprimary endpoints that compare success in the weaning of third-line agents and resolution of potentially life-threatening status epilepticus with brexanolone vs. placebo when added to standard-of-care … In particular, the use of brexanolone in treating PPD is surrounded with promise because it acts in part as a synthetic supplement for possible deficiencies in endogenous brexanolone (allopregnanolone)