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Displaying results 1481 - 1490 of 2828 in total
  1. Drug

    Tetraethylammonium

    go.drugbank.com/drugs/DB08837
    Investigational

    Tetraethylammonium is an experimental drug with no approved indication or marketed formulation. The only marketed drug containing tetraethylammonium was a combination drug called Fosglutamina B6, but this drug has now been discontinued. ...

    Categories: Membrane Transport Modulators
  2. Drug

    Dequalinium

    go.drugbank.com/drugs/DB04209
    Approved

    Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic...

    Categories: Genito Urinary System and Sex Hormones
  3. Drug

    CYNK-001

    go.drugbank.com/drugs/DB15722
    Investigational

    CYNK-001 is a novel allogenic off-the-shelf natural killer (NK) cell therapy originating from human placental CD34+ hematopoietic stem cells and enriched with CD56+/CD3-.

  4. Drug

    Skin-derived ABCB5-positive Mesenchymal Stem cells

    go.drugbank.com/drugs/DB17862
    Investigational

    Skin-derived ABCB5-positive Mesenchymal Stem cells are under investigation in clinical trial NCT04971161 (Allogeneic Abcb5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase Iib)).

    Synonyms: Skin-derived ABCB5+ Mesenchymal Stem cells, Skin-derived ABCB5-positive Mesenchymal Stem cells
  5. Drug

    Anti-CD7 CAR-T

    go.drugbank.com/drugs/DB23322
    Investigational

    CD7 CAR-T is under investigation in clinical trial NCT07117305 (CD7 CAR-T Combined With Autologous Hematopoietic Stem Cell Transplantation).

  6. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

    go.drugbank.com/bio_entities/BE0000089
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-15 kDa
  7. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    the ALLHAT trial confirmed the role of thiazide diuretics as first-line therapy and demonstrated that chlorthalidone had a statistically significant lower incidence of stroke and heart failure when compared

    Mixtures: ATENOLOL AL COMP, ATENOLOL AL COMPCategories: Membrane Transport Modulators
  8. Drug

    AEM-28

    go.drugbank.com/drugs/DB17642
    Investigational

    AEM-28 is a 28 amino acid mimetic of apolipoprotein E being investigated for lipid disorders, such as homozygous familial hypercholesterolemia. It possesses anti-inflammatory properties.[A258764]

    Synonyms: AEM 28, AEM-28
  9. Target

    Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

    go.drugbank.com/bio_entities/BE0020167
    EnzymeHumans

    Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins (PubMed:11677243).

    Synonyms: Core 1 beta3-Gal-T1, Core 1 O-glycan T-synthase
  10. Drug

    Terodiline

    go.drugbank.com/drugs/DB13725
    Experimental

    Categories: Membrane Transport Modulators, Genito Urinary System and Sex Hormones