Search
Elranatamab
go.drugbank.com/drugs/DB15395ApprovedInvestigational[L47815] On August 14, 2023, the FDA granted accelerated approval to elranatamab for the treatment of multiple myeloma. … Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager.
Iodoform
go.drugbank.com/drugs/DB13813ApprovedInvestigationalVet approvedWithdrawnSince the beginning of the 20th century, iodoform has been commonly used as a healing and antiseptic dressing or powder for wounds and sores, however such clinical use to this date is limited. … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry.
Chloroform
go.drugbank.com/drugs/DB11387ApprovedVet approvedWithdrawnChloroform is part of the FDA drug products withdrawn or removed from the market for reasons of safety or effectiveness.[L43942] … It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigerants, but the latter application is declining.
Synonyms: chloroformium pro narcosiCategories: Compounds used in a research, industrial, or household settingUrsodeoxycholic acid
go.drugbank.com/drugs/DB01586ApprovedInvestigational[A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years. … Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool.
Products: URSO 1A PHARMA 250MG, URSO 1A PHARMA 400MGPegaspargase
go.drugbank.com/drugs/DB00059ApprovedInvestigational[A103,A255912,L44667] Pegaspargase has the same mechanism of action as [L-asparaginase] derived from _Escherichia coli_, a previously developed enzyme used for the treatment of acute lymphoblastic … [A255912,A255917] In February 1994, pegaspargase was approved by the FDA for the treatment of ALL in patients with hypersensitivity to native forms of L-asparaginase.[A255927]
Categories: Compounds used in a research, industrial, or household settingSynonyms: PEG-L-Asparaginase, Peg/L-asparaginasePixantrone
go.drugbank.com/drugs/DB06193ApprovedWithdrawnIt will compare pixantrone efficacy to that of gemcitabine. [2] … Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL.
Leuprolide
go.drugbank.com/drugs/DB00007ApprovedInvestigational[L13781, L13790] Leuprolide remains frontline therapy in all conditions for which it is indicated for use. … Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH).
Products: LUPRON ® DEPOT 11.25 MG POLVO LIOFILIOZADO PARA RECONSTITUIR A SUSPENSIÓN INYECTABLE, POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mgChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnIt is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Categories: Antihistamines for Topical Use, Antihistamines for Systemic UsePrezatide
go.drugbank.com/drugs/DB11296ApprovedPrezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions [A19503]. Prezatide is used in cosmetic products for the skin and hair.
Synonyms: Glycyl-L-histidyl-L-lysineIslatravir
go.drugbank.com/drugs/DB15653ApprovedInvestigational[A275490, A275492] Because it is a substrate for deoxycytidine kinase (dCK), its efficacy can be compromised by co-administration with other dCK substrates like lamivudine or emtricitabine, which are consequently … Islatravir is a first-in-class, highly potent nucleoside reverse transcriptase translocation inhibitor (NRTTI) used in combination therapy for the treatment of HIV-1 infection.