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Displaying results 141 - 150 of 2950 in total
  1. Drug

    Veligrotug

    go.drugbank.com/drugs/DB18976
    Approved

    Veligrotug is a humanized IgG1 monoclonal antibody that binds the insulin-like growth factor-1 receptor and blocks ligand-induced receptor autophosphorylation, interrupting IGF-1R signaling.

    Categories: Insulin-like Growth Factor-1 Receptor InhibitorSynonyms: Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human-Mus musculus monoclonal VRDN-001 γ1-chain), disulfide with human-Mus musculus monoclonal VRDN-001 κ-chain, dimer, Immunoglobulin G1-kappa, anti-[Homo sapiens IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)], chimeric monoclonal antibody (gamma1 heavy chain chimeric (1-454) [VH (Mus musculus IGHV1S81
  2. Drug

    Spironolactone

    go.drugbank.com/drugs/DB00421
    ApprovedInvestigational

    [A178192] It promotes sodium and water excretion and potassium retention.

    Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 InhibitorsProducts: SPIRONOLACTON 100MG AAA PH
  3. Drug

    ALLO-715

    go.drugbank.com/drugs/DB18640
    Investigational

    ALLO-715 is an allogeneic chimeric antigen receptor T Cell therapy targeting B cell maturation antigen (BCMA).

    Synonyms: Allogenic Chimeric Antigen Receptor T Cells Targeting B Cell Maturation Antigen (BCMA)
  4. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Mixtures: LORZAAR PL FORTE100/12.5MGCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Griseofulvin

    go.drugbank.com/drugs/DB00400
    ApprovedVet approved

    An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersProducts: Fulvicin P/G 165, Fulvicin Pg Tab 330mg
  6. Drug

    Amiodarone

    go.drugbank.com/drugs/DB01118
    ApprovedInvestigational

    Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpat...

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: AMIODARONE PH&T
  7. Drug

    AD-114

    go.drugbank.com/drugs/DB18285
    Experimental

    Synonyms: Human single domain antibody-like protein inhibitor of the chemokine receptor type 4
  8. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina, and was the first calcium channel antagonist to be introduced into therapy in the early 1960s. It is a m...

    Categories: Adrenergic alpha-1 Receptor Antagonists, P-glycoprotein inhibitorsProducts: Verelan PM, Verapamil Hydrochloride PM
  9. Drug

    RAD 502

    go.drugbank.com/drugs/DB17328
    Experimental

    Synonyms: Lutetium-177 labeled humanized monoclonal antibody targeting leucine rich repeat containing 15 (LRRC15)
  10. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer