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Rituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigational[A40017, L146018] Rituximab was originally approved by the U.S. … FDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL), and has since been approved for a variety of conditions.[L4811] On November 28, 2018, the U.S.
Products: RITOXEN 10MG/ML, IXIMAB® 10MG/MLAflibercept
go.drugbank.com/drugs/DB08885ApprovedInvestigational[L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023. … [A261130,L47915] Ziv-aflibercept, under the brand name Zaltrap, was developed as an intravenous injection for the treatment of metastatic colorectal cancer, and it was approved by the FDA and EMA in
Products: EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIAL, Yesafili 40mg/mL solution for injection in a vialGuanethidine
go.drugbank.com/drugs/DB01170ApprovedWithdrawnIt is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.
Products: Guanethidine 10 Tab 10mg, Apo Guanethidine Sulfate Tab 10mgDexamethasone
go.drugbank.com/drugs/DB01234ApprovedInvestigationalVet approved[L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and [prednisolone].[A188724] Dexamethasone was granted FDA approval on 30 October 1958. … Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic
Mixtures: Ducressa (Dexamethasone 1mg/ml + Levofloxacin 5mg/ml) eye drops, solution, Ducressa (Dexamethasone 1mg/ml + Levofloxacin 5mg/ml) eye drops, solutionProducts: PMS-dexamethasone Sod Phosphate Inj 10mg/ml, Hexadrol Phosphate Inj 10mg/mlFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalIt is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.
Products: FLUVASTATIN - CT 20MG HART, FLUVASTATIN - CT 40MG HARTGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalIt is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs. … It is commonly marketed under the brand name Amaryl as oral tablets and is typically administered once daily.
Mixtures: GLIMET 1mg/500mg SUSTAINED RELEASE TABLETS, AMARYL®M 2MG/1000MGProducts: GLIMEPIRID - CT 1MG, GLIMEPIRID HEUMANN 1MG NETFamotidine
go.drugbank.com/drugs/DB00927ApprovedInvestigationalIt is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. … about 20 to 50 times more potent at inhibiting gastric acid secretion than [cimetidine] and eight times more potent than [ranitidine] on a weight basis.
Mixtures: ETOPLUS 400MG/8MG/20MG FİLM KAPLI TABLET, 14 ADET, ETOFAM 400MG/20MG FİLM KAPLI TABLET, 20 ADETProducts: Famotidine 10mg, Pepcid I.V. 10mg/mlDiethylstilbestrol
go.drugbank.com/drugs/DB00255ApprovedWithdrawnIt was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. … (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose.[L43942]
Synonyms: (E)-3,4-bis(4-hydroxyphenyl)-3-hexene, α,α'-diethyl-(E)-4,4'-stilbenediolProducts: Stilbestrol Tab 1mg, Honvol Ampoules 250mgDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Products: VOMETA FT TABLET 10MG, DOMPERIDON - CT 10MG FILMTHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigational[A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
Products: PMS Hydroxyzine Cap 10mg, PMS Hydroxyzine Syr 10mg/5ml