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Levosalbutamol
go.drugbank.com/drugs/DB13139Approved[Salbutamol] has been marketed as a racemic mixture, although beta2-agonist activity resides almost exclusively in the (R)-enantiomer. … The enantioselective disposition of salbutamol and the possibility that (S)-salbutamol has adverse effects have led to the development of an enantiomerically pure (R)-salbutamol formulation known as levosalbutamol
Mixtures: İPRALEV 20 MCG/50 MCG AEROSOL İNHALASYONU,SÜSPANSİYON, 200 DOZCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsCiprofloxacin
go.drugbank.com/drugs/DB00537ApprovedInvestigationalCiprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics. … [L6469,L6472,L6475,L6478,L6481,L6484,L6487,L6490,L6493] The first ciprofloxacin containing product was FDA approved on 22 October 1987.[L6463]
Mixtures: ORNISASIN 500 MG/500 MG FILM TABLET, 10 ADET, ORCIPOL 500 MG/500 MG FILM TABLET, 10 ADETCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A InhibitorsDesmopressin
go.drugbank.com/drugs/DB00035ApprovedInvestigationalDesmopressin, also known as 1-deamino-8-D-arginine vasopressin (DDAVP), is a synthetic analogue of the natural posterior pituitary hormone arginine vasopressin (AVP) [A275458, L56105]. … It was designed through two primary chemical modifications of the natural hormone: the deamination of 1-cysteine and the substitution of L-arginine with D-arginine at the 8th position [A31661, A275458]
Products: NOCDURNA 50 MCG ORAL LYOPHILISATE, MINIRIN 0,1 MG TABLET, 100 ADETPotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedPotassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste.
Mixtures: Q-10 Plus, C-1000 Plus Zinc & PotassiumProducts: UROCIT-K(5 MEQ) 540 MG 100 KONTROLLU SALIM TABLETI, UROCIT-K(10 MEQ) 1080 MG 100 KONTROLLU SALIM TABLETINivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigational[A35203] It was developed by Bristol Myers Squibb.[L12129] Nivolumab was granted FDA approval on 22 December 2014. … [L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability and reduced variability.
Categories: Immunoglobulin GProducts: OPDIVO CONCENTRATE FOR SOLUTION FOR INFUSION 10 MG/ML, OPDIVO 100 INF. IÇIN KONS. IÇEREN FLAKON, 1 ADETPaclitaxel
go.drugbank.com/drugs/DB01229ApprovedInvestigationalVet approvedUsed as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel … It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane.
Synonyms: -HYDROXY-, (2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3, 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersAtenolol
go.drugbank.com/drugs/DB00335ApprovedInvestigationalAtenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981.
Mixtures: TENORETIC 100 MG/25 MG FILM TABLET, 28 ADET, TENORETIC 50 MG/12.5 MG FILM TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesEtoposide
go.drugbank.com/drugs/DB00773ApprovedInvestigationalA semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair b...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-oneAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib has been used in trials studying the treatment of melanoma, lymphoma, neoplasm, solid tumor, and glioblastoma. … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with [DB00947].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: YULAREB 100 MG FİLM KAPLI TABLET, 56 ADET, VERZENIO® 100 MGChlorpromazine
go.drugbank.com/drugs/DB00477ApprovedInvestigationalVet approvedChlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Synonyms: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine, 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amineCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT2 Receptor Antagonists