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Displaying results 141 - 150 of 2517 in total
  1. Drug

    Retifanlimab

    go.drugbank.com/drugs/DB15766
    ApprovedInvestigational

    death-ligand 2 (PD-L2). … Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed

    Synonyms: Anti-PD-1 monoclonal antibody MGA012Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors
  2. Indication

    Itching caused by Nettles

    go.drugbank.com/conditions/DBCOND0134233
    Drugs: Tripelennamine
    Synonyms: Itching caused by Nettles
  3. Drug

    Carbamazepine

    go.drugbank.com/drugs/DB00564
    ApprovedInvestigational

    Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, ...

    Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: CARBAMAZEPIN 200 1A PH
  4. Drug

    Lobeline

    go.drugbank.com/drugs/DB05137
    Investigational

    An alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, a...

  5. Drug

    Formoterol

    go.drugbank.com/drugs/DB00983
    ApprovedInvestigational

    Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racem...

    Mixtures: SYMBICORT PI 80/4.5UG120ED, SYMBICORT PI 80/4.5UG120EDCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
  6. Drug

    Ibuprofen

    go.drugbank.com/drugs/DB01050
    ApprovedInvestigational

    Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics. The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in ...

    Synonyms: (±)-p-isobutylhydratropic acid, (±)-2-(p-isobutylphenyl)propionic acidMixtures: Advil PM, Advil PM
  7. Drug

    Allantoin

    go.drugbank.com/drugs/DB11100
    ApprovedInvestigational

    Allantoin is a substance that is endogenous to the human body and also found as a normal component of human diets [FDA Label]. In healthy human volunteers, the mean plasma concentration of allantoin is about 2-3 mg/l. During exercise, th...

    Products: Dr Young 2p Blemish Base SPF35 PA, Young 2P Pearl Brightening Balm SPF35 PA
  8. Drug

    Elagolix

    go.drugbank.com/drugs/DB11979
    ApprovedInvestigational

    In particular, estimates suggest that one in ten women of reproductive age is affected by endometriosis and experience debilitating pain symptoms [A35868, A35869, F801]. … Moreover, women who are affected by this condition can suffer for up to six to ten years and visit multiple physicians before receiving a proper diagnosis [A35868, A35869, F801].

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
  9. Drug

    Toripalimab

    go.drugbank.com/drugs/DB15043
    ApprovedInvestigational

    One mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1)[A261506] - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the inhibition … [L48681] Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against the PD-1 receptor.

    Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors
  10. Drug

    4-Methoxyamphetamine

    go.drugbank.com/drugs/DB01472
    ExperimentalIllicit

    Synonyms: P-methoxyamfetamine, P-methoxyamphetamineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates