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Simoctocog alfa
go.drugbank.com/drugs/DB09108ApprovedFull human post-translational modifications via elimination of potentially immunogenic glycosylation patterns found in non-human cell lines led to decreased immunogenicity and longer half-life [A31525]
Vosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigationalEndogenous CNP, first described in 1998, is primarily responsible for the stimulation of chondrocytes and long bone growth via activity at the NPR-B receptor, making it an attractive target in the treatment
Sapropterin
go.drugbank.com/drugs/DB00360ApprovedInvestigationalconversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via
Tisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigationala tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting agent, via
Malacidin B
go.drugbank.com/drugs/DB14052ExperimentalMalacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears to act via its own distinct mechanism.
Malacidin A
go.drugbank.com/drugs/DB14051ExperimentalMalacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears to act via its own distinct mechanism.
Lactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedA normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and ...
Mixtures: Ringer-Lactat nach Hartmann B.Braun Infusionslösung, Ringer-Lactat nach Hartmann NORIDEM InfusionslösungTestosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigational[L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone.
Ichthammol
go.drugbank.com/drugs/DB11341ApprovedIt is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed by sulfonation and neutralization.