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Octinoxate
go.drugbank.com/drugs/DB09496ApprovedInvestigationalIt was originally developed in 1950's as an organic UV-B filter that absorbs UV-B rays from sun. … Octinoxate is a cinnamate ester and common ingredient in sunscreen and other skin care products to minimize DNA photodamage.
Mixtures: Fluide Éclat Du Jour SPF 15, Nu Skin Nu Colour Tinted Moisturizer Broad Spectrum SPF 15 SandCategories: Compounds used in a research, industrial, or household settingLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalHowever, this is no longer recommended for the majority of patients due to several clinical concerns including limited controlled trials supporting its use. … Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland.
Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETASCategories: UGT1A1 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 InhibitorsAzelaic acid
go.drugbank.com/drugs/DB00548ApprovedInvestigationalAzelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. … It is also produced by _Malassezia furfur_, also known as _Pityrosporum ovale_, which is a species of fungus that is normally found on human skin.
Mixtures: Azelaic Acid 15% / Niacinamide 4%Products: Finacea 150 mg/g Gel, FINACEA JEL % 15, 30 GAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigational[A18262] This is beneficial in the treatment of ADHD as DA activation in the subcortical NA and striatum is associated with many stimulant-associated side effects and an increase in abuse potential, which … [A178090] Atomoxetine has been shown to specifically increase NA and DA within the prefrontal cortex, but not in the nucleus accumbens (NA) or striatum.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: Ag-atomoxetine, ATOMOXETIN AL 10MG HKPSomatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigational[A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names. … [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa.
Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im ScCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersPhenobarbital
go.drugbank.com/drugs/DB01174ApprovedInvestigationalA barbituric acid derivative that acts as a nonselective central nervous system depressant.
Mixtures: PIROFEN 200 MG/15 MG SUPPOZITUAR, 50 ADET, PIROFEN 200 MG/15 MG SUPPOZITUAR, 10 ADETCategories: Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexFlecainide
go.drugbank.com/drugs/DB01195ApprovedInvestigationalWithdrawn[A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. … [A186931] It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexProducts: TAMBOCOR (TABLET 100 MG), TAMBOCOR TABLET 100 mgRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalHowever there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Ag-rivaroxaban, RIVAROXABAN DR. REDDY'SFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Mixtures: FULDUO 100 MG/8 MG FİLM KAPLI TABLET, 14 ADET, MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesMiconazole
go.drugbank.com/drugs/DB01110ApprovedVet approvedMiconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well. … [A214523, L14021] It is currently available as a variety of prescription and over the counter products.
Mixtures: EXAGYN 750 MG/250 MG/100 MG VAJİNAL TABLET, MIXOVUL 750 MG/200 MG/100 MG OVÜL, 7 OVÜLCategories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP2B6 Inhibitors