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Latanoprostene bunod
go.drugbank.com/drugs/DB11660ApprovedIn comparison, both latanoprost and latanoprostene bunod contain a latanoprost acid backbone. … or ocular hypertension.
Azficel-T
go.drugbank.com/drugs/DB11051ApprovedWithdrawnExpanded cells are then suspended in a cell medium. … As a replacement for lost dermal constituents in the aging or skin deformation process, treatment with autologous fibroblasts has shown to improve wrinkle and acne scar appearance than with placebo treatment
Vepdegestrant
go.drugbank.com/drugs/DB19006ApprovedInvestigational[A275508] Specifically, vepdegestrant is being developed as a first-line or subsequent treatment option for patients whose tumors grow in response to estrogen and have progressed after standard therapies … Vepdegestrant is a potent, selective, and orally bioavailable PROteolysis TArgeting Chimera (PROTAC) small molecule estrogen receptor (ER) degrader.
Denosumab
go.drugbank.com/drugs/DB06643ApprovedInvestigationalfor fracture receiving adjuvant aromatase inhibitor therapy for breast cancer in September 2011 and in men with osteoporosis at high risk for fracture in September 2012. … [A263066] An Denosumab biosimilar, Jubbonti, was approved for Health Canada in February 2024.[L52083].
Categories: Drugs for Treatment of Bone DiseasesProducts: XGEVA 120mg Solution for Injection, XGEVA Solution for Injection 120 mg/vialCysteine
go.drugbank.com/drugs/DB00151ApprovedInvestigationalNutraceuticalA thiol-containing non-essential amino acid that is oxidized to form cystine.
Mixtures: VitaHealth L-Glutathione Plus, AMINOSTERIL N-HEPA FOR INTRAVENOUS INFUSION 8%Synonyms: L-Cys, L-CysteinHypochlorite
go.drugbank.com/drugs/DB11123ApprovedInvestigationalHypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. … Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite.
Categories: Compounds used in a research, industrial, or household settingProducts: NaOClean E-WaterTetraferric tricitrate decahydrate
go.drugbank.com/drugs/DB14520ApprovedInvestigationalTetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. … [A25965] Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.[L9926]
Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaAcetrizoic acid
go.drugbank.com/drugs/DB09347ApprovedWithdrawn[L1704] Acetrizoic acid presents, in the FDA records, a category of drug substance with an inactive status.[L1703] … [A32135] It was first synthesized by Wallingford in 1953[A32136] and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th, 1978.
Categories: Compounds used in a research, industrial, or household settingRifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigationalRifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.
Synonyms: 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetateMixtures: PRO TB 4, PRO TB 2Belzutifan
go.drugbank.com/drugs/DB15463ApprovedInvestigational[L36105] Initially considered to be undruggable, a binding pocket was eventually discovered in the HIF-2α molecule which allowed for compounds to bind and inhibit these proteins. … [L35995] The HIF-2α protein was first identified in the 1990s by researchers at UT Southwestern Medical Center as a key player in the growth of certain cancers.