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Etoricoxib Action Pathway (New)
smpdb.ca/view/SMP0122862Drug actionIt specifically targets the prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. … The cyclooxygenase pathway begins in the cytosol with phospholipids being converted into arachidonic acid by the action of phospholipase A2.
Enzymes: Prostaglandin E synthaseLumiracoxib NSAID Action Pathway
smpdb.ca/view/SMP0124453Drug actionIt selectively targets the prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. … Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthaseMefenamic Acid NSAID Action Pathway
smpdb.ca/view/SMP0124586Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase. … Cytokines are produced in the central nervous system (CNS) during an inflammatory response.
Enzymes: Prostaglandin E synthasePiroxicam NSAID Action Pathway
smpdb.ca/view/SMP0124588Drug actionIt targets the prostaglandin G/H synthase-1 (COX-1) and prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. … The cyclooxygenase pathway begins in the cytosol with phospholipids being converted into arachidonic acid by the action of phospholipase A2.
Enzymes: Prostaglandin E synthaseTenoxicam Action Pathway (New)
smpdb.ca/view/SMP0124589Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase. … Because tenoxicam decreases PGE2 in the CNS, it has an antipyretic effect.
Enzymes: Prostaglandin E synthaseSalicylic Acid COX Action Pathway
smpdb.ca/view/SMP0124590Drug actionSalicylate's use in rheumatic diseases is due to it's analgesic and anti-inflammatory activity. … Prostaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase, or prostaglandin E2 via prostaglandin E synthase.
Enzymes: Prostaglandin E synthaseIndomethacin NSAID Action Pathway
smpdb.ca/view/SMP0124592Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase. … Because indomethacin decrease PGE2 in the CNS, it has an antipyretic effect.
Enzymes: Prostaglandin E synthaseNaproxen NSAID Action Pathway
smpdb.ca/view/SMP0124612Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase. … Cytokines are produced in the central nervous system (CNS) during an inflammatory response.
Enzymes: Prostaglandin E synthaseDiflunisal NSAID Action Pathway
smpdb.ca/view/SMP0124631Drug actionProstaglandin H2 can either be converted into thromboxane A2 via thromboxane A synthase, prostacyclin/prostaglandin I2 via prostacyclin synthase or prostaglandin E2 via prostaglandin E synthase. … Cytokines are produced in the central nervous system (CNS) during an inflammatory response.
Enzymes: Prostaglandin E synthaseAceclofenac Action Pathway
smpdb.ca/view/SMP0124997Drug actionAceclofenac targets the prostaglandin G/H synthase-1 (COX-1) and prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. … The cyclooxygenase pathway begins in the cytosol with phospholipids being converted into arachidonic acid by the action of phospholipase A2.
Drugs: Glutathione · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 · Arachidonic Acid +1 moreEnzymes: Prostaglandin E synthase