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Displaying results 1501 - 1510 of 10000 in total
  1. Drug

    Ergotamine

    go.drugbank.com/drugs/DB00696
    Approved

    A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.

    Mixtures: CAFERGOT 1 MG/100 MG TABLET, 30 ADET, ERGOTAMINA 1 MG + CAFEINA 100 MG TABLETASProducts: Ergafein 150 mg/60 mg/0.25 mg Kaplı Tablet, Ergomar Slt 2mg
  2. Drug

    ABO-202

    go.drugbank.com/drugs/DB16976
    Experimental

  3. Drug

    MTI-201

    go.drugbank.com/drugs/DB17169
    Investigational

    Synonyms: MTI 201
  4. Drug

    TCN-202

    go.drugbank.com/drugs/DB17777
    Investigational

    Synonyms: TCN-202 (human anti-cytomegalovirus monoclonal antibody)
  5. Drug

    Fludrocortisone

    go.drugbank.com/drugs/DB00687
    ApprovedInvestigational

    Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency.

    Products: ASTONIN-H 0,1 MG TABLET, 100 ADET, FLORINEF TABLET 0.1 mg
  6. Drug

    Ecallantide

    go.drugbank.com/drugs/DB05311
    Approved

    Apart from its FDA and EMA indication, ecallantide has been used off label in the management of nonhistaminergic angioedema, not due to HAE [A32017]. … By reversibly binding to plasma kallikrein, ecallantide displays a rapid on-rate and a slow off-rate that results in high affinity inhibition in the picomolar range [L1458].

    Categories: Drugs Used in Hereditary AngioedemaProducts: KALBITOR® 10 MG / ML
  7. Drug

    Chlorprothixene

    go.drugbank.com/drugs/DB01239
    ApprovedInvestigationalWithdrawn

    Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors.

    Categories: Dopamine D2 Receptor AntagonistsProducts: Truxal 15 mg - Filmtabletten, Truxal 50 mg - Filmtabletten
  8. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    In 2009, vinflunine was approved by the European Medicines Agency (EMA) as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment [A32626]. … Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396].

    Synonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastineProducts: Javlor Concentrate for Solution for Infusion 25 mg/mL
  9. Drug

    Enfuvirtide

    go.drugbank.com/drugs/DB00109
    ApprovedInvestigational

    The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.

    Categories: Gene Products, env, env Gene Products, Human Immunodeficiency VirusProducts: FUZEON POLVO SOLUCION INYECTABLE 90 MG/MI
  10. Drug

    Fomepizole

    go.drugbank.com/drugs/DB01213
    ApprovedVet approved

    Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. … Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes the initial steps in the metabolism of ethylene glycol and methanol to their toxic metabolites.

    Categories: Compounds used in a research, industrial, or household settingProducts: Fomepizol SERB 5 mg/ml Konzentrat zur Herstellung einer Infusionslösung