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Amifampridine
go.drugbank.com/drugs/DB11640ApprovedPatients with LEMS develop serum antibodies against presynaptic P/Q-type voltage-gated calcium channels, leading to decreased presynaptic calcium levels and reduced quantal release of acetylcholine, which … Amifampridine phosphate is a more stable salt that serves as an active ingredient of EMA-approved Firdapse, which was previously marketed as Zenas.
Categories: Heterocyclic Compounds, 1-RingHT-0712
go.drugbank.com/drugs/DB11650InvestigationalBLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
Categories: Heterocyclic Compounds, 1-RingDactolisib
go.drugbank.com/drugs/DB11651InvestigationalDactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRebamipide
go.drugbank.com/drugs/DB11656ApprovedInvestigationalRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingQAV-680
go.drugbank.com/drugs/DB11658InvestigationalQAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis.
Categories: Heterocyclic Compounds, 2-RingPsilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Categories: Heterocyclic Compounds, 2-RingSP-8203
go.drugbank.com/drugs/DB11670InvestigationalSP-8203 has been used in trials studying the treatment of Ischemic Stroke.
Categories: Heterocyclic Compounds, 2-RingAZD-4877
go.drugbank.com/drugs/DB11671InvestigationalAZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
Categories: Heterocyclic Compounds, 1-RingEquol
go.drugbank.com/drugs/DB11674InvestigationalEquol has been used in trials studying the treatment of Breast Cancer.
Synonyms: S-equolCategories: Heterocyclic Compounds, 2-RingPF-06282999
go.drugbank.com/drugs/DB11683InvestigationalPf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects).
Categories: Heterocyclic Compounds, 1-Ring