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Eszopiclone
go.drugbank.com/drugs/DB00402ApprovedInvestigationalEszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. … It is the active stereoisomer of zopiclone, belonging to the class of drugs known as _cyclopyrrolones_.
Synonyms: (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate, (+)-(5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl-4-methylpiperazine-1-carboxylateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEntacapone
go.drugbank.com/drugs/DB00494ApprovedInvestigationalWhen administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration … Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols.
Synonyms: (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide, N,N-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl) acrylamideMixtures: ANTIPAR 200 MG/50 MG/200 MG FILM KAPLI TABLET, 100 ADET, STALEVO 200/50/200 MG 100 FILM KAPLI TABLETTrametinib
go.drugbank.com/drugs/DB08911ApprovedInvestigational[A258298] It was later approved by Health Canada on July 18, 2013 [L45588] and by the European Commission on June 30, 2014. … [L45583] Trametinib is currently approved to treat a variety of cancers with BRAF mutations, such as non-small cell lung cancer and thyroid cancer, as monotherapy or in combination with [dabrafenib], a
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MEKINIST 0.5 MG FILM KAPLI TABLET ,TABLET, 30 ADET, MEKINIST 2 MG FILM KAPLI TABLET ,TABLET, 30 ADETBenzoyl peroxide
go.drugbank.com/drugs/DB09096ApprovedInvestigational[L33314] After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.
Mixtures: OXIMIN 10 MG/G + 50 MG/G JEL,50 G, OXIMIN 10 MG/G + 50 MG/G JEL,25 GProducts: TRİAKNE %10 EMÜLSİYON JEL, 50 G, Panoxyl Wash 10 - Liq Top 10%Pomalidomide
go.drugbank.com/drugs/DB08910ApprovedInvestigationalPomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: POMALYST 1 MG, POMALYST 2 MGalpha-Tocopherol succinate
go.drugbank.com/drugs/DB14001ApprovedNutraceuticalVet approvedThe recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
Mixtures: PreQue 10, Vitamine E 400 Ui and Selenium 50Products: M-Vegmax22, Webber Vitamin E Liq 77unit/ml Water SolAlanyl glutamine
go.drugbank.com/drugs/DB11876InvestigationalAlanyl Glutamine is under investigation in clinical trial NCT00338221 (Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition).
Products: DİPEPİTVEN %20 İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ, 100 ML, GLUTAVIVEN 20 G/100 ML IV INF. ICIN KONSANTRE COZELTI İÇEREN FLAKONSorafenib
go.drugbank.com/drugs/DB00398ApprovedInvestigational[A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also indicated to treat renal carcinoma and differentiated thyroid carcinoma
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: NEXAVAR TABLET 200 mg, Sorafenib TEVA 200 mg FilmtablettenDoxapram
go.drugbank.com/drugs/DB00561ApprovedInvestigationalVet approvedA central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Products: RESDOX 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, Dopram Inj 20mg/mlClodronic acid
go.drugbank.com/drugs/DB00720ApprovedInvestigationalVet approved[A203111] Clodronic acid is not FDA approved, but is approved in Canada.[L13910] … Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid].
Products: BONEFOS 800 MG TABLET, 60 ADET, Lodronat 520 mg - Filmtabletten