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Iopanoic acid
go.drugbank.com/drugs/DB08946ApprovedWithdrawnIopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Categories: Diagnostic Uses of Chemicals, Compounds used in a research, industrial, or household settingPamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigational[A203111] Pamidronic acid was granted FDA approval on 31 October 1991.[L13835]
Categories: Drugs for Treatment of Bone DiseasesProducts: Pamidronate Disodium Omega 6 mg/ml, Pamidronate Disodium Omega 9 mg/mlInsulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigationalof basal insulin over 42 hours with a low peak: trough ratio. … Use of basal and bolus insulin together is intended to mimic the pancreas' production of endogenous insulin, with the goal of avoiding any periods of hypoglycemia.
Methylnaltrexone
go.drugbank.com/drugs/DB06800ApprovedInvestigationalMethylnaltrexone is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation without producing analgesic effects or withdrawal symptoms.
Categories: Heterocyclic Compounds with 4 or More RingsAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism of alpha-adrenergic and 5-HT2A receptors. … [L45859,A4393] Aripiprazole was given FDA approval on November 15, 2002.[L6136]
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ABILIFY 5 MG, Arileto 10 mg-TablettenEthionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnIt also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Categories: Drugs for Treatment of TuberculosisProducts: ETIONAMIDA TABLETAS 250 MG, ETYOMID 250 MG DRAJE, 50 ADETDesipramine
go.drugbank.com/drugs/DB01151ApprovedIn depressed individuals, desipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. … See toxicity section below for a complete listing of side effects.
Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: DESIPRAM 25 MG TABLET, 100 ADETGlofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigational, after two or more lines of systemic therapy under accelerated approval based on response rate and durability of response. … ) after two or more lines of systemic therapy.
Toripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalThe proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance. … of T-cell proliferation and cytokine production, and thus its overexpression can inhibit T-cell-mediated immune surveillance of tumors.
Nitrous acid
go.drugbank.com/drugs/DB09112ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. … Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning.
Categories: Compounds used in a research, industrial, or household setting