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Displaying results 1521 - 1530 of 10000 in total
  1. Drug

    DA-8031

    go.drugbank.com/drugs/DB19024
    Investigational

    DA-8031 is under investigation in clinical trial NCT01798667 (Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation).

    Synonyms: 1-(3-(DIMETHYLAMINO)PROPYL)-1,3-DIHYDRO-1-(4-METHOXYPHENYL)-5-ISOBENZOFURANCARBONITRILE, 5-ISOBENZOFURANCARBONITRILE, 1-(3-(DIMETHYLAMINO)PROPYL)-1,3-DIHYDRO-1-(4-METHOXYPHENYL)-Categories: Heterocyclic Compounds, 2-Ring
  2. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    [L13571] It is therefore not considered to be a disease-modifying drug. … It also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance.

    Mixtures: GALNORA 8MG + 16MG HKP RET, GALNORA 8MG + 16MG HKP RETCategories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitors
  3. Drug

    Citrulline

    go.drugbank.com/drugs/DB00155
    InvestigationalNutraceutical

    It is made from ornithine and carbamoyl phosphate in one of the central reactions in the urea cycle. It is also produced from arginine as a by-product of the reaction catalyzed by NOS family. … Its name is derived from citrullus, the Latin word for watermelon, from which it was first isolated.

    Synonyms: 2-Amino-5-ureidovaleric acid, (S)-2-Amino-5-ureidopentanoic acidProducts: STIMOL ORAL SOLUTION 1g/10ml
  4. Drug

    SB 224289

    go.drugbank.com/drugs/DB17052
    Experimental

    SB-224289 is a small molecule with a high affinity for human 5-HT1B receptors.[A253122]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: (4-(2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)phenyl)-(1'-methylspiro(6,7-dihydro-2h-furo(2,3-f)indole-3,4'-piperidine)-5-yl)methanone, (2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-(1,1'-biphenyl)-4-yl)(1'-methyl-6,7-dihydrospiro(furo(2,3-f)indole-3,4'-piperidin)-5(2h)-yl)methanone
  5. Drug

    Ivermectin

    go.drugbank.com/drugs/DB00602
    ApprovedInvestigationalVet approved

    [L31453] Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1a</sub>) and 10% 5-O-demethyl-25-de … (1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A<sub>1a</sub> (22,23-dihydroavermectin B<sub>1b</sub>).

    Mixtures: Heartgard Plus Chewable Tablet for Dogs - 26 - 50 lbs, Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbsCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  6. Drug

    Rezafungin

    go.drugbank.com/drugs/DB16310
    ApprovedInvestigational

    Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily. … [L45633,L45658] It was subsequently approved in the EU in November of the same year. [L52745]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Echinocandin B, 1-((4R,5R)-4-hydroxy-N2-((4''-(pentyloxy)(1,1':4',1''-terphenyl)-4-yl)carbonyl)-5-(2-(trimethylammonio)ethoxy)-l-ornithine)-4-((4S)-4-hydroxy-4-(4-hydroxyphenyl)-l-allothreonine)-
  7. Drug

    Iron protein succinylate

    go.drugbank.com/drugs/DB11209
    Approved

    Mixtures: FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET, KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 20 FLK.Products: KOMFER 40 MG ORAL ÇÖZELTİ, 15 ML X 20 FLAKON, FERBEST 40 MG/15 ML ORAL COZELTI ,20 FLAKON
  8. Drug

    Brinzolamide

    go.drugbank.com/drugs/DB01194
    Approved

    [A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse … [L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320]

    Mixtures: AZARGA 10 MG/ML + 5 MG/ML, BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADETCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 Substrates
  9. Drug

    Sibutramine

    go.drugbank.com/drugs/DB01105
    ApprovedIllicitWithdrawn

    It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SEROTRAMIN CAPSULAS 20 MG., OBESTOPPOR 5 MG CAPSULAS
  10. Drug

    PD-169316

    go.drugbank.com/drugs/DB17040
    Experimental

    PD-169316 is a p38 MAP kinase inhibitor.[A253062]

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1h-imidazole, Pyridine, 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1h-imidazol-5-yl)-